MARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, Laboratório Marítimo da Guia, Faculdade de Ciências, Universidade de Lisboa, 2750-005 Lisbon, Portugal.
IPMA-Portuguese Institute for the Ocean and Atmosphere, Av. Alfredo Magalhães Ramalho, n° 6, 1495-165 Lisbon, Portugal.
Mar Drugs. 2022 Sep 23;20(10):594. doi: 10.3390/md20100594.
Tetrodotoxin (TTX) is a potent neurotoxin naturally occurring in terrestrial and marine organisms such as pufferfish. Due to the risk of TTX poisoning, fish of Tetraodontidae family and other puffer-related species must not be placed in the EU markets. This restriction applies to fish of the family Molidae even though no data on toxins' occurrence is available. In this study, the presence of TTX and its analogues was investigated in the main edible tissue (the white muscle) and the main xenobiotics storage organ (the liver) of ocean sunfish spp. ( = 13) from the South Portuguese coast. HILIC-MS/MS analyses did not reveal TTX in the analyzed samples, suggesting an inexistent or very limited risk of TTX poisoning.
河豚毒素 (TTX) 是一种存在于陆地和海洋生物中的强效神经毒素，如河豚鱼。由于 TTX 中毒的风险，属于 Tetraodontidae 科的鱼类和其他与河豚有关的物种不得进入欧盟市场。即使没有关于毒素存在的数据，这种限制也适用于 Molidae 科的鱼类。在这项研究中，对来自葡萄牙南部海岸的海洋翻车鱼属物种（= 13）的主要可食用组织（白色肌肉）和主要异生素储存器官（肝脏）中的 TTX 及其类似物的存在进行了调查。亲水相互作用色谱-串联质谱分析未在分析样品中发现 TTX，表明 TTX 中毒的风险不存在或非常有限。
