Department of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Korea.
Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam 13488, Korea.
Mar Drugs. 2022 Sep 27;20(10):607. doi: 10.3390/md20100607.
Okamura (ES) is mainly distributed in the coastal areas of the middle Pacific, around Korea and Japan, and has a long-standing edible value. It is rich in various compounds, such as polysaccharides, fatty acids, alginic acid, fucoxanthin, and phlorotannins, among which the polyphenol compound phlorotannins are the main active ingredients. Studies have shown that the extracts and active components of ES exhibit anti-cancer, antioxidant, anti-obesity, anti-diabetic, antibacterial, cardioprotective, immunomodulatory, and other pharmacological properties in vivo and in vitro. Although ES contains a variety of bioactive compounds, it is not widely known and has not been extensively studied. Based on its potential health benefits, it is expected to play an important role in improving the nutritional value of food both economically and medically. Therefore, ES needs to be better understood and developed so that it can be utilized in the development and application of marine medicines, functional foods, bioactive substances, and in many other fields. This review provides a comprehensive overview of the bioactivities and bioactive compounds of ES to promote in-depth research and a reference for the comprehensive utilization of ES in the future.
Okamura（海蕴）主要分布于中太平洋沿海地区、朝鲜半岛及日本周边海域，具有悠久的食用价值。它富含多种化合物，如多糖、脂肪酸、褐藻酸、岩藻黄素和缩酚酸等，其中多酚化合物缩酚酸是主要的活性成分。研究表明，ES 的提取物和活性成分在体内和体外具有抗癌、抗氧化、抗肥胖、抗糖尿病、抗菌、心脏保护、免疫调节等药理作用。尽管 ES 含有多种生物活性化合物，但它并不广为人知，也没有得到广泛研究。基于其潜在的健康益处，它有望在经济和医学上提高食品的营养价值方面发挥重要作用。因此，需要更好地了解和开发 ES，以便将其应用于海洋药物、功能性食品、生物活性物质等的开发和应用。本综述提供了 ES 的生物活性和生物活性化合物的全面概述，以促进对 ES 的深入研究，并为 ES 在未来的综合利用提供参考。
