Mgbejime Goodness Temofe, Hossin Md Altab, Nneji Grace Ugochi, Monday Happy Nkanta, Ekong Favour
School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China.
School of Innovation and Entrepreneurship, Chengdu University, Chengdu 610106, China.
Diagnostics (Basel). 2022 Oct 13;12(10):2484. doi: 10.3390/diagnostics12102484.
Today, Magnetic Resonance Imaging (MRI) is a prominent technique used in medicine, produces a significant and varied range of tissue contrasts in each imaging modalities, and is frequently employed by medical professionals to identify brain malignancies. With brain tumor being a very deadly disease, early detection will help increase the likelihood that the patient will receive the appropriate medical care leading to either a full elimination of the tumor or the prolongation of the patient's life. However, manually examining the enormous volume of magnetic resonance imaging (MRI) images and identifying a brain tumor or cancer is extremely time-consuming and requires the expertise of a trained medical expert or brain doctor to manually detect and diagnose brain cancer using multiple Magnetic Resonance images (MRI) with various modalities. Due to this underlying issue, there is a growing need for increased efforts to automate the detection and diagnosis process of brain tumor without human intervention. Another major concern most research articles do not consider is the low quality nature of MRI images which can be attributed to noise and artifacts. This article presents a Contrast Limited Adaptive Histogram Equalization (CLAHE) algorithm to precisely handle the problem of low quality MRI images by eliminating noisy elements and enhancing the visible trainable features of the image. The enhanced image is then fed to the proposed PCNN to learn the features and classify the tumor using sigmoid classifier. To properly train the model, a publicly available dataset is collected and utilized for this research. Additionally, different optimizers and different values of dropout and learning rates are used in the course of this study. The proposed PCNN with Contrast Limited Adaptive Histogram Equalization (CLAHE) algorithm achieved an accuracy of 98.7%, sensitivity of 99.7%, and specificity of 97.4%. In comparison with other state-of-the-art brain tumor methods and pre-trained deep transfer learning models, the proposed PCNN model obtained satisfactory performance.
如今,磁共振成像(MRI)是医学中一项重要的技术,在每种成像模式下都能产生大量且多样的组织对比度,并且经常被医学专业人员用于识别脑肿瘤。脑肿瘤是一种非常致命的疾病,早期检测将有助于提高患者接受适当医疗护理的可能性,从而实现肿瘤的完全消除或延长患者的生命。然而,人工检查大量的磁共振成像(MRI)图像并识别脑肿瘤或癌症极其耗时,并且需要训练有素的医学专家或脑科医生的专业知识,以便使用多种不同模式的磁共振图像(MRI)手动检测和诊断脑癌。由于这个潜在问题,越来越需要加大努力,在无需人工干预的情况下实现脑肿瘤检测和诊断过程的自动化。大多数研究文章未考虑的另一个主要问题是MRI图像的低质量特性,这可能归因于噪声和伪影。本文提出了一种对比度受限自适应直方图均衡化(CLAHE)算法,通过消除噪声元素并增强图像的可见可训练特征,精确地处理低质量MRI图像的问题。然后将增强后的图像输入到所提出的脉冲耦合神经网络(PCNN)中,以学习特征并使用 sigmoid 分类器对肿瘤进行分类。为了正确训练模型,收集了一个公开可用的数据集并用于本研究。此外,在本研究过程中使用了不同的优化器以及不同的随机失活(dropout)值和学习率。所提出的带有对比度受限自适应直方图均衡化(CLAHE)算法的脉冲耦合神经网络(PCNN)实现了98.7%的准确率、99.7%的灵敏度和97.4%的特异性。与其他最先进的脑肿瘤方法和预训练的深度迁移学习模型相比,所提出的脉冲耦合神经网络(PCNN)模型取得了令人满意的性能。