Department of ICT Convergence, The Graduate School, Soonchunhyang University, Asan 31538, Korea.
Department of Occupational Therapy, Soonchunhyang University, Asan 31538, Korea.
Int J Environ Res Public Health. 2022 Oct 12;19(20):13096. doi: 10.3390/ijerph192013096.
If the negative emotions experienced in life become trauma, they affect daily life. Neuro-feedback technology has recently been introduced as a treatment, but many different neuro-feedback protocols and methods exits. This study conducted a meta-analysis of neuro-feedback training for post-traumatic stress disorder (PTSD) symptoms to evaluate the effects of functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG)-based neuro-feedback training. A search of PubMed, the Cochrane Library, Web of Science, Science Direct, and ClinicalTrials.gov was conducted from January 2011 to December 2021. The studies' quality was assessed using the Cochrane risk of bias tool and publication bias was assessed by Egger's regression test. Seven studies that met the inclusion criteria were used for the systematic review and meta-analysis. EEG was more effective than fMRI for PTSD symptoms, and the effect on PTSD symptoms was higher than on anxiety and depression. There was no difference in the effectiveness of the training sessions. Our findings showed that EEG-based neuro-feedback training was more helpful for training PTSD symptoms. Additionally, the methods were also shown to be valid for evaluating clinical PTSD diagnoses. Further research is needed to establish a gold standard protocol for the EEG-based neuro-feedback training (EEG-NFT) method for PTSD symptoms.
如果生活中经历的负面情绪成为创伤，它们会影响日常生活。神经反馈技术最近被引入作为一种治疗方法，但存在许多不同的神经反馈协议和方法。本研究对创伤后应激障碍（PTSD）症状的神经反馈训练进行了荟萃分析，以评估功能磁共振成像（fMRI）和基于脑电图（EEG）的神经反馈训练的效果。从 2011 年 1 月至 2021 年 12 月，对 PubMed、Cochrane 图书馆、Web of Science、Science Direct 和 ClinicalTrials.gov 进行了搜索。使用 Cochrane 偏倚风险工具评估研究质量，并通过 Egger 回归检验评估发表偏倚。有 7 项符合纳入标准的研究用于系统评价和荟萃分析。与 fMRI 相比，EEG 对 PTSD 症状更有效，对 PTSD 症状的效果高于焦虑和抑郁。训练次数的效果没有差异。我们的研究结果表明，基于 EEG 的神经反馈训练对 PTSD 症状的训练更有帮助。此外，这些方法也被证明可用于评估临床 PTSD 诊断。需要进一步的研究来建立 PTSD 症状的基于 EEG 的神经反馈训练（EEG-NFT）方法的金标准协议。
