Medical School, University of Zagreb, Zagreb, Croatia.
Health Center Zagreb West.
Acta Clin Croat. 2022 Jun;61(Suppl 1):23-27. doi: 10.20471/acc.2022.61.s1.03.
The aim of this study was to determine the frequency of newly verified or worsened existing hypertension in patients who had coronavirus 2019 (COVID-19). To be categorized as a COVID-19 patient, a positive reverse-transcription polymerase chain reaction test at a single point in time was required. The patients' age, history, laboratory values and antihypertensive therapy of patients were recorded. In one year, 32 of 199 patients studied had either newly verified (15) or worsened existing (17) arterial hypertension. Among those patients, the median time from a verified infection to the onset of symptoms was 3 months. When the patients were divided into groups, 4 were in the acute, 11 in the sub-acute, 8 in the chronic and 9 in the "long COVID" group. Compared to the rest of the study population, patients presenting with arterial hypertension had significantly higher systolic (median 141 mmHg vs 130 mmHg, p<0.001) and diastolic (median 93 mmHg vs 80 mmHg, p<0.001) blood pressure and were significantly younger (median 51 vs 59 years, p 0.032). Arterial hypertension following COVID-19, either newly verified or worsened existing, is a relatively common occurrence (16% of our patient pool), indicating that more effort should be directed at evaluating the blood pressure values of patients following COVID-19.
本研究的目的是确定在感染 2019 年冠状病毒（COVID-19）的患者中新确诊或现有高血压恶化的频率。要被归类为 COVID-19 患者，需要在单点进行阳性逆转录聚合酶链反应测试。记录了患者的年龄、病史、实验室值和降压治疗。在一年内，199 名患者中有 32 名新确诊（15 名）或原有高血压恶化（17 名）。在这些患者中，从确诊感染到出现症状的中位时间为 3 个月。当患者分为几组时，4 名处于急性期，11 名处于亚急性期，8 名处于慢性期，9 名处于“长新冠”期。与研究人群的其余部分相比，出现高血压的患者收缩压（中位数 141mmHg 与 130mmHg，p<0.001）和舒张压（中位数 93mmHg 与 80mmHg，p<0.001）显著更高，年龄也显著更轻（中位数 51 岁与 59 岁，p<0.032）。COVID-19 后新发或原有高血压是一种相对常见的现象（占我们患者群体的 16%），这表明应投入更多精力评估 COVID-19 后患者的血压值。
