Miao Mengrong, Han Yaqian, Wang Yangyang, Yang Yitian, Zhu Ruilou, Sun Mingyang, Zhang Jiaqiang
Department of Anesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, People's Hospital of Henan University, Zhengzhou, Henan, China.
Front Pharmacol. 2022 Oct 18;13:1014550. doi: 10.3389/fphar.2022.1014550. eCollection 2022.
Ferroptosis is a newly proposed concept of programmed cell death and has been widely studied in many diseases during the past decade. However, a bibliometric study that concentrates on publication outputs and research trends of ferroptosis related to the brain is lacking. We retrieved publication data in the field of ferroptosis in the brain from the Web of Science Core Collection on 31 December 2021. A bibliometric analysis was performed using VOSviewer and CiteSpace software. Six hundred fifty-six documents focusing on ferroptosis in the brain were published from 2012 to 2021. The number of publications in this field has shown a steady increase in recent years. Most publications were from China (338) and the United States (166), while the most productive organizations were at the University of Melbourne (34) and University of Pittsburgh (23). Ashley I. Bush was the most productive author, while Scott J Dixon was the most co-cited author. The journal Free Radical Biology and Medicine published the most articles in this field, while Cell was the most cited journal. Among 656 publications, top 10 cited documents were cited at least 300 times. Among the top 20 references with the strongest citation bursts, half of the papers had a burst until 2021. The keywords analysis suggests that the top 20 keywords appeared at least 40 times. Additionally, "amyloid precursor protein" was the keyword with strongest bursts. Research on ferroptosis in the brain will continue to be highly regarded. This study analyzed the research landscape of ferroptosis in the brain and offers a new reference for researchers in this field.
铁死亡是一种新提出的程序性细胞死亡概念，在过去十年中已在许多疾病中得到广泛研究。然而，目前缺乏一项专注于与大脑相关的铁死亡的出版物产出和研究趋势的文献计量学研究。我们于2021年12月31日从科学网核心合集中检索了大脑铁死亡领域的出版物数据。使用VOSviewer和CiteSpace软件进行了文献计量分析。2012年至2021年期间发表了656篇专注于大脑铁死亡的文献。近年来，该领域的出版物数量呈稳步增长趋势。大多数出版物来自中国（338篇）和美国（166篇），而产出最多的机构是墨尔本大学（34篇）和匹兹堡大学（23篇）。阿什利·I·布什是产出最多的作者，而斯科特·J·迪克森是被引用最多的作者。《自由基生物学与医学》杂志在该领域发表的文章最多，而《细胞》杂志是被引用最多的期刊。在656篇出版物中，被引用次数排名前10的文献至少被引用了300次。在引用爆发最强的前20篇参考文献中，一半的论文在2021年之前出现了爆发。关键词分析表明，前20个关键词至少出现了40次。此外，“淀粉样前体蛋白”是爆发最强的关键词。大脑铁死亡的研究将继续受到高度关注。本研究分析了大脑铁死亡的研究概况，为该领域的研究人员提供了新的参考。
