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饮食与代谢综合征:一篇叙述性综述。

Diet and metabolic syndrome: a narrative review.

作者信息

Angelico Francesco, Baratta Francesco, Coronati Mattia, Ferro Domenico, Del Ben Maria

机构信息

Department of Clinical Internal, Anaesthesiological and Cardiovascular Sciences, I Clinica Medica, Sapienza University of Rome, Policlinico Umberto 1, 00161, Rome, Italy.

出版信息

Intern Emerg Med. 2023 Jun;18(4):1007-1017. doi: 10.1007/s11739-023-03226-7. Epub 2023 Mar 16.

Abstract

Metabolic syndrome (MetS) is a highly prevalent condition defined by the presence of at least three out of five risk factors including central obesity, increased fasting glucose, high blood pressure, and dyslipidaemia. Metabolic syndrome is associated with a 2-fold increase in cardiovascular outcomes and a 1.5-fold increase in all-cause mortality. Excess energy intake and Western dietary pattern may influence the development of metabolic syndrome. By contrast, both Mediterranean diet (Med-diet) and Dietary Approaches to Stop Hypertension (DASH) diet, with or without calorie restriction, have positive effects. For the prevention and management of MetS, it is recommended to increase the daily intake of fiber-rich and low-glycaemic-index foods and the consumption of fish and dairy products, especially yogurt and nuts. Moreover, it is advisable to consume a large variety of unprocessed cereals, legumes, and fruit. Finally, it is suggested to replace saturated fatty acids with monounsaturated and polyunsaturated fatty acids and to limit the consumption of free sugars to less than 10% of the total energy intake. The aim of this narrative review is to analyze current evidence on the different dietary patterns and nutrients that may affect prevention and treatment of MetS and to discuss the underlying pathophysiological mechanisms.

摘要

代谢综合征(MetS)是一种高度普遍的病症,由五个危险因素中的至少三个存在来定义,这五个危险因素包括中心性肥胖、空腹血糖升高、高血压和血脂异常。代谢综合征与心血管疾病风险增加两倍以及全因死亡率增加1.5倍相关。能量摄入过多和西方饮食模式可能会影响代谢综合征的发展。相比之下,地中海饮食(Med-diet)和得舒饮食(DASH),无论有无热量限制,都有积极作用。对于代谢综合征的预防和管理,建议增加富含纤维和低血糖指数食物的每日摄入量,以及鱼类和乳制品的摄入量,尤其是酸奶和坚果。此外,宜食用多种未加工的谷物、豆类和水果。最后,建议用单不饱和脂肪酸和多不饱和脂肪酸替代饱和脂肪酸,并将游离糖的摄入量限制在总能量摄入的10%以下。本叙述性综述的目的是分析关于可能影响代谢综合征预防和治疗的不同饮食模式和营养素的现有证据,并讨论潜在的病理生理机制。

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