Sakamornchai Wirada, Dumrongwongsiri Oraporn, Siwarom Sirinapa
Division of Nutrition, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Front Nutr. 2022 Oct 20;9:928026. doi: 10.3389/fnut.2022.928026. eCollection 2022.
Children with developmental and behavioral problems including autistic spectrum disorders (ASDs) may have inappropriate feeding behaviors, which leads to an increased risk of multiple nutrient deficiencies. Vitamin C deficiency is one of the common nutrient deficiencies reported in children with inappropriate feeding. This case report illustrates two cases of ASD children with a clinical presentation of pulmonary arterial hypertension, a rare presentation of vitamin C deficiency. Vitamin C supplementation, pulmonary vasodilator, and supportive treatment were provided. Patients could recover from the illness and could be discharged from the hospital in a short time. In addition to vitamin C, the patients also had multiple micronutrient deficiencies. Nutrition counseling was given and micronutrient supplement was continued until follow-up. Regular nutrition assessment and counseling among children with ASD are needed to prevent nutrient deficiencies which may lead to life-threatening complications.
患有包括自闭症谱系障碍（ASD）在内的发育和行为问题的儿童可能会有不适当的喂养行为，这会增加多种营养素缺乏的风险。维生素C缺乏是喂养不当的儿童中常见的营养素缺乏之一。本病例报告阐述了两例患有肺动脉高压临床表现的自闭症谱系障碍儿童，这是维生素C缺乏的一种罕见表现。给予了维生素C补充、肺血管扩张剂和支持性治疗。患者能够康复并在短时间内出院。除了维生素C缺乏外，患者还存在多种微量营养素缺乏。给予了营养咨询，并持续补充微量营养素直至随访。需要对自闭症谱系障碍儿童进行定期的营养评估和咨询，以预防可能导致危及生命并发症的营养素缺乏。
