Zheng Senwang, Liu Songtao, Hou Ajiao, Wang Song, Na Yexin, Hu Jianhua, Jiang Hai, Yang Liu
Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin, China.
Front Pharmacol. 2022 Oct 19;13:1013992. doi: 10.3389/fphar.2022.1013992. eCollection 2022.
Lonicerae Japonicae Flos has been used as a tea and medicine for more than 1,500 years. It has the functions of clearing heat, detoxification, and is often used to treat carbuncle, furuncle, throat arthralgia, erysipelas, heat-toxic blood dysentery, febrile fever. This paper summarizes the botany, ethnopharmacology, chemical composition and pharmacological action of Lonicerae Japonicae Flos from 1986 to 2022, and looks forward to the future research direction of Lonicerae Japonicae Flos. At present, the components isolated from Lonicerae Japonicae Flos include essential oils, organic acids, flavonoids, iridoids, saponins and other compounds. It has the effects of anti-inflammation, anti-virus, anti-bacteria, anti-oxidation, anti-tumor, protect liver and galltesticles, hypotensive, hypolipidemic, anti-thrombosis, anti-allergy, immune regulation and so on. It is often used in clinical treatment of diarrhea, hematochezia, febrile disease, exogenous wind-heat, and cold, swelling and toxin of carbuncle, sore throat and so on. The comprehensive evaluation of the quality of Lonicerae Japonicae Flos and the understanding of multi-target network pharmacology also need to be studied. As a kind of health food with high value, LJF is worthy of further promotion and development.
金银花作为茶和药物已有1500多年的历史。它具有清热、解毒的功效，常用于治疗痈、疖、咽喉肿痛、丹毒、热毒血痢、发热等病症。本文综述了1986年至2022年金银花的植物学、民族药理学、化学成分和药理作用，并展望了金银花未来的研究方向。目前，从金银花中分离出的成分包括挥发油、有机酸、黄酮类、环烯醚萜类、皂苷类等化合物。它具有抗炎、抗病毒、抗菌、抗氧化、抗肿瘤、保护肝脏和胆囊、降压、降脂、抗血栓、抗过敏、免疫调节等作用。常用于临床治疗腹泻、便血、热病、外感风热、感冒、痈肿疮毒、咽喉肿痛等。金银花质量的综合评价以及多靶点网络药理学的认识也有待研究。金银花作为一种具有高价值的保健食品，值得进一步推广和开发。
