Huo Yehong, Hu Jian, Yin Yuanyuan, Liu Peng, Cai Kaiyong, Ji Wei
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, P. R. China.
Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, P. R. China.
Chembiochem. 2023 Jan 17;24(2):e202200582. doi: 10.1002/cbic.202200582. Epub 2022 Nov 30.
Peptides can self-assemble into various hierarchical nanostructures through noncovalent interactions and form functional materials exhibiting excellent chemical and physical properties, which have broad applications in bio-/nanotechnology. The self-assembly mechanism, self-assembly morphology of peptide supramolecular architecture and their various applications, have been widely explored which have the merit of biocompatibility, easy preparation, and controllable functionality. Herein, we introduce the latest research progress of self-assembling peptide-based nanomaterials and review their applications in biomedicine and optoelectronics, including tissue engineering, anticancer therapy, biomimetic catalysis, energy harvesting. We believe that this review will inspire the rational design and development of novel peptide-based functional bio-inspired materials in the future.
肽可以通过非共价相互作用自组装成各种层次的纳米结构，并形成具有优异化学和物理性质的功能材料，这些材料在生物/纳米技术中具有广泛的应用。肽超分子结构的自组装机制、自组装形态及其各种应用已得到广泛探索，它们具有生物相容性好、易于制备和功能可控的优点。在此，我们介绍了基于肽的自组装纳米材料的最新研究进展，并综述了它们在生物医学和光电子学中的应用，包括组织工程、抗癌治疗、仿生催化、能量收集。我们相信，这篇综述将激发未来新型基于肽的功能性生物启发材料的合理设计和开发。
