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慢性肾脏病的死亡率与生活质量:一项针对初始接受腹膜透析样本的五年队列研究

Mortality and Quality of Life with Chronic Kidney Disease: A Five-Year Cohort Study with a Sample Initially Receiving Peritoneal Dialysis.

作者信息

Sitjar-Suñer Miquel, Suñer-Soler Rosa, Bertran-Noguer Carme, Masià-Plana Afra, Romero-Marull Natalia, Reig-Garcia Glòria, Alòs Francesc, Patiño-Masó Josefina

机构信息

Primary Health Centre, Institut Català de la Salut, 17800 Olot, Spain.

Nursing Department, University of Girona, 17003 Girona, Spain.

出版信息

Healthcare (Basel). 2022 Oct 28;10(11):2144. doi: 10.3390/healthcare10112144.

DOI:10.3390/healthcare10112144
PMID:36360484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9690964/
Abstract

UNLABELLED

The quality of life, morbidity and mortality of people receiving renal replacement therapy is affected both by the renal disease itself and its treatment. The therapy that best improves renal function and quality of life is transplantation.

OBJECTIVES

To study the quality of life, morbidity and mortality of people receiving renal replacement therapy over a five-year period.

DESIGN

A longitudinal multicentre study of a cohort of people with chronic kidney disease.

METHODS

Patients from the Girona health area receiving peritoneal dialysis were studied, gathering data on sociodemographic and clinical variables through an ad hoc questionnaire, quality of life using the SF-36 questionnaire, and social support with the MOS scale.

RESULTS

Mortality was 47.2%. Physical functioning was the variable that worsened most in comparison with the first measurement ( = 0.035). Those receiving peritoneal dialysis ( = 0.068) and transplant recipients ( = 0.083) had a better general health perception. The social functioning of transplant recipients improved ( = 0.008).

CONCLUSIONS

People with chronic kidney disease had a high level of mortality. The dimension of physical functioning worsens over the years. Haemodialysis is the therapy that most negatively effects general health perception. Kidney transplantation has a positive effect on the dimensions of energy/vitality, social functioning and general health perception.

摘要

未标注

接受肾脏替代治疗的患者的生活质量、发病率和死亡率受肾脏疾病本身及其治疗的影响。能最佳改善肾功能和生活质量的治疗方法是移植。

目的

研究接受肾脏替代治疗的患者在五年期间的生活质量、发病率和死亡率。

设计

对一组慢性肾病患者进行纵向多中心研究。

方法

对来自赫罗纳健康区接受腹膜透析的患者进行研究,通过专门设计的问卷收集社会人口统计学和临床变量数据,使用SF-36问卷评估生活质量,并用MOS量表评估社会支持。

结果

死亡率为47.2%。与首次测量相比,身体功能是恶化最严重的变量(P = 0.035)。接受腹膜透析的患者(P = 0.068)和移植受者(P = 0.083)对总体健康状况的感知更好。移植受者的社会功能有所改善(P = 0.008)。

结论

慢性肾病患者死亡率较高。身体功能维度多年来有所恶化。血液透析是对总体健康状况感知负面影响最大的治疗方法。肾移植对精力/活力、社会功能和总体健康状况感知维度有积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01a/9690964/2eab2f898c99/healthcare-10-02144-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01a/9690964/2a2b39d60b80/healthcare-10-02144-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01a/9690964/2eab2f898c99/healthcare-10-02144-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01a/9690964/2a2b39d60b80/healthcare-10-02144-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01a/9690964/2eab2f898c99/healthcare-10-02144-g002a.jpg

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本文引用的文献

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Nefrologia (Engl Ed). 2021 Jul-Aug;41(4):461-466. doi: 10.1016/j.nefroe.2021.10.006. Epub 2021 Nov 4.
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Achieved blood pressure post-acute kidney injury and risk of adverse outcomes after AKI: A prospective parallel cohort study.急性肾损伤后血压达标与 AKI 后不良结局风险:一项前瞻性平行队列研究。
BMC Nephrol. 2021 Jul 29;22(1):270. doi: 10.1186/s12882-021-02480-1.
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Burden of Chronic Kidney Disease by KDIGO Categories of Glomerular Filtration Rate and Albuminuria: A Systematic Review.
慢性肾脏病的负担按 KDIGO 肾小球滤过率和蛋白尿类别分类:系统评价。
Adv Ther. 2021 Jan;38(1):180-200. doi: 10.1007/s12325-020-01568-8. Epub 2020 Nov 24.
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Surgical versus percutaneous catheter placement for peritoneal dialysis: an updated systematic review and meta-analysis.手术与经皮导管置管在腹膜透析中的应用:更新的系统评价和荟萃分析。
J Nephrol. 2021 Oct;34(5):1681-1696. doi: 10.1007/s40620-020-00896-w. Epub 2020 Nov 16.
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Chronic kidney disease is a very significant comorbidity for high risk of death in patients with COVID-19 in Mexico.慢性肾脏病是墨西哥 COVID-19 患者死亡风险极高的一个非常重要的合并症。
Nephrology (Carlton). 2021 Mar;26(3):248-251. doi: 10.1111/nep.13827. Epub 2020 Nov 22.
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Can J Kidney Health Dis. 2020 Oct 19;7:2054358120957431. doi: 10.1177/2054358120957431. eCollection 2020.
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Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29013-29024. doi: 10.1073/pnas.2005905117. Epub 2020 Nov 3.
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