Institute for Health and Sport, Victoria University, Melbourne, VIC 3011, Australia.
Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago 7591538, Chile.
Nutrients. 2022 Oct 28;14(21):4531. doi: 10.3390/nu14214531.
Several studies have explored the effects of capsaicin and capsiate on endurance performance, with conflicting findings. This systematic review aimed to perform a meta-analysis examining the effects of capsaicin and capsiate vs. placebo on endurance performance in humans. Seven databases were searched to find eligible studies. The effects of capsaicin and capsiate on aerobic endurance (e.g., time-trials or time-to-exhaustion tests), muscular endurance (e.g., repetitions performed to muscular failure), and rating of perceived exertion (RPE) were examined in a random-effects meta-analysis. Fourteen studies ( = 183) were included in the review. Most studies provided capsaicin or capsiate in the dose of 12 mg, 45 min before exercise. In the meta-analysis for aerobic endurance, there was no significant difference between the placebo and capsaicin/capsiate conditions (Cohen's : 0.04; 95% confidence interval: -0.16, 0.25; = 0.69). In subgroup meta-analyses, there were no significant differences between the placebo and capsaicin/capsiate conditions when analyzing only studies that used time-trials ( = 0.20) or time-to-exhaustion tests ( = 0.80). In the meta-analysis for muscular endurance, a significant ergogenic effect of capsaicin/capsiate was found (Cohen's : 0.27; 95% confidence interval: 0.10, 0.43; = 0.002). When analyzing set-specific effects, an ergogenic effect of capsaicin/capsiate was found in set 1, set 2, and set 3 (Cohen's : 0.21-29). Capsaicin/capsiate ingestion reduced RPE following muscular endurance ( = 0.03) but not aerobic endurance tests ( = 0.58). In summary, capsaicin/capsiate supplementation acutely enhances muscular endurance, while the effects on aerobic endurance are less clear.
几项研究探讨了辣椒素和辣椒素对耐力表现的影响，结果存在冲突。本系统评价旨在进行荟萃分析，以检查辣椒素和辣椒素与安慰剂相比对人体耐力表现的影响。通过七个数据库搜索发现符合条件的研究。使用随机效应荟萃分析检查了辣椒素和辣椒素对有氧耐力（例如，时间试验或力竭时间测试）、肌肉耐力（例如，肌肉衰竭时的重复次数）和感知用力程度（RPE）的影响。纳入了 14 项研究（n = 183）。大多数研究在运动前 45 分钟给予 12 毫克的辣椒素或辣椒素。在有氧耐力的荟萃分析中，安慰剂和辣椒素/辣椒素条件之间没有显著差异（Cohen's ：0.04；95%置信区间：-0.16，0.25； = 0.69）。在亚组荟萃分析中，当仅分析使用时间试验（ = 0.20）或力竭时间测试（ = 0.80）的研究时，安慰剂和辣椒素/辣椒素条件之间没有显著差异。在肌肉耐力的荟萃分析中，发现辣椒素/辣椒素具有显著的增强作用（Cohen's ：0.27；95%置信区间：0.10，0.43； = 0.002）。在分析特定集合的效果时，发现辣椒素/辣椒素在集合 1、集合 2 和集合 3 中具有增强作用（Cohen's ：0.21-29）。辣椒素/辣椒素摄入可降低肌肉耐力后的 RPE（ = 0.03），但不降低有氧耐力测试后的 RPE（ = 0.58）。总之，辣椒素/辣椒素补充剂可急性增强肌肉耐力，而对有氧耐力的影响则不太明确。
