Rafnsson V, Jóhannesdóttir S G
Br J Ind Med. 1986 Aug;43(8):522-5. doi: 10.1136/oem.43.8.522.
An investigation was carried out to determine the cause of death among 450 masons in Iceland who had been exposed to hexavalent chromium, a trace element in cement. The cohort was defined as all men born between 1905 and 1945 who had, according to the Register of Masons and Stone-cutters, finished vocational training as masons. For deaths occurring between 1951 and 1982 information was obtained from the Statistical Bureau of Iceland. Expected death rates were calculated, based on the national rates for men in the corresponding age groups. The total number of deaths from all causes was less than expected for the whole study period (81 v 85.86) but, with a 20 year latent period, 58 deaths were found against 50.57 expected; with a 30 year latent period, 38 deaths were found against 27.82 expected, which may, to a large extent, be accounted for by an excess of deaths from lung cancer. Nine deaths from lung cancer were found in the cohort, eight with 20 and 30 year latent periods compared with expected rates of 2.87, 2.19, and 1.28 respectively. The results seem to indicate that the increased number of deaths from lung cancer among the masons has a causal relation to occupational exposure.
开展了一项调查,以确定冰岛450名接触六价铬(水泥中的一种微量元素)的泥瓦匠的死因。该队列定义为所有1905年至1945年出生、根据泥瓦匠和石匠登记册已完成泥瓦匠职业培训的男性。对于1951年至1982年期间发生的死亡事件,信息来自冰岛统计局。根据相应年龄组男性的全国死亡率计算预期死亡率。在整个研究期间,所有原因导致的死亡总数低于预期(81例对85.86例),但在20年潜伏期时,发现58例死亡,预期为50.57例;在30年潜伏期时,发现38例死亡,预期为27.82例,这在很大程度上可能是由于肺癌死亡人数过多所致。该队列中发现9例肺癌死亡,其中8例有20年和30年潜伏期,预期发生率分别为2.87、2.19和1.28。结果似乎表明,泥瓦匠中肺癌死亡人数的增加与职业接触存在因果关系。