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冰岛化肥制造商的死亡率研究。

Mortality study of fertiliser manufacturers in Iceland.

作者信息

Rafnsson V, Gunnarsdóttir H

机构信息

Department of Occupational Medicine, Administration of Occupational Safety and Health, Reykjavík, Iceland.

出版信息

Br J Ind Med. 1990 Nov;47(11):721-5. doi: 10.1136/oem.47.11.721.

Abstract

A retrospective cohort study was carried out on workers in a fertiliser plant to assess the risk of stomach and lung cancer. The cohort comprised 603 subjects and their death rates were compared with those of the general male population in Iceland. The study period was 1954 to 1985. The results do not provide evidence of an excess of deaths from stomach or lung cancer. Total mortality was lower than expected and even lower when the analysis was restricted to those who had worked at the plant for more than one year. Shiftwork operators had the highest SMRs for all cancers, however, with a reverse dose response according to duration of employment, indicating that this might be due to factors unrelated to manufacture of fertilisers. As examples of these factors life style and social class may be implicated, as well as possible selection of weaker subjects to do this assumed easy work.

摘要

对一家化肥厂的工人进行了一项回顾性队列研究,以评估胃癌和肺癌的风险。该队列由603名受试者组成,并将他们的死亡率与冰岛男性总人口的死亡率进行了比较。研究期间为1954年至1985年。结果未提供胃癌或肺癌死亡人数过多的证据。总死亡率低于预期,当分析仅限于在该厂工作超过一年的人时,死亡率甚至更低。然而,轮班工人的所有癌症标准化死亡比最高,且根据就业时长呈现反向剂量反应,这表明这可能是由于与化肥生产无关的因素所致。这些因素可能包括生活方式和社会阶层,以及可能选择了身体较弱的受试者从事这份被认为轻松的工作。

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