The Skin Wounds and Trauma Research Centre, The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland.
The Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland.
Qual Life Res. 2023 Jul;32(7):1843-1857. doi: 10.1007/s11136-022-03310-z. Epub 2022 Dec 1.
To ascertain the impact of home non-invasive ventilation (NIV) on the health-related quality of life (HRQL) of patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
Systematic review.
A preliminary search of computerised databases (CINAHL, Medline, Clinical Key, Cochrane) was conducted in June 2021, without any limitations on publication date. Inclusion criteria focused on home NIV prescribed for patients with moderate-to-severe COPD. Identified papers were critically appraised for rigour and validity. Data were extracted, analysed, and a narrative synthesis completed.
The review included eight studies, including five randomised controlled trials. Variations in the HRQL scores meant that the data were difficult to collate. Nevertheless, the studies did indicate an overall improved HRQL for those using NIV at home.
This systematic review determines that home NIV does positively impact the HRQL of those with COPD. However, the limited quality of primary studies highlights the need for more in-depth research in this area to bring about optimal standardisation of clinical practice in relation to the use of NIV at home.
确定家庭无创通气（NIV）对中重度慢性阻塞性肺疾病（COPD）患者健康相关生活质量（HRQL）的影响。
系统评价。
2021 年 6 月，对计算机数据库（CINAHL、Medline、Clinical Key、Cochrane）进行了初步检索，对发表日期没有任何限制。纳入标准主要集中在为中重度 COPD 患者开具的家庭 NIV 上。对确定的论文进行了严格性和有效性的批判性评估。提取数据、分析数据并完成叙述性综合。
综述纳入了 8 项研究，其中包括 5 项随机对照试验。HRQL 评分的差异意味着数据难以整理。尽管如此，这些研究确实表明，在家中使用 NIV 的患者的 HRQL 总体上有所改善。
这项系统评价确定家庭 NIV 确实对 COPD 患者的 HRQL 产生积极影响。然而，初级研究质量有限突出表明，需要在这一领域进行更深入的研究，以实现家庭使用 NIV 的临床实践的最佳标准化。
