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Front Immunol. 2022 Sep 9;13:971866. doi: 10.3389/fimmu.2022.971866. eCollection 2022.
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Antigen presentation by Follicular Dendritic cells to cognate B cells is pivotal for Generalised Modules for Membrane Antigens (GMMA) immunogenicity.滤泡树突状细胞向同源 B 细胞呈递抗原对于广义膜抗原（GMMA）的免疫原性至关重要。
Vaccine. 2022 Oct 19;40(44):6305-6314. doi: 10.1016/j.vaccine.2022.09.034. Epub 2022 Sep 20.
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Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines.紧急情况下的调整：N1-甲基假尿苷在新冠疫苗中的作用
ACS Cent Sci. 2021 May 26;7(5):748-756. doi: 10.1021/acscentsci.1c00197. Epub 2021 Apr 6.
4
Antibodies Elicited by the GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension.成人 GMMA 疫苗引发的抗体触发补体介导的血清杀菌活性：一项 1 期剂量递增试验的结果，随后进行了加强剂扩展。
Front Immunol. 2021 May 4;12:671325. doi: 10.3389/fimmu.2021.671325. eCollection 2021.
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Paratyphi A Outer Membrane Vesicles Displaying Vi Polysaccharide as a Multivalent Vaccine against Enteric Fever.甲型副伤寒 A 外膜囊泡展示 Vi 多糖作为肠热病多价疫苗。
Infect Immun. 2021 Mar 17;89(4). doi: 10.1128/IAI.00699-20.
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Adjuvant effect of TLR7 agonist adsorbed on aluminum hydroxide (AS37): A phase I randomized, dose escalation study of an AS37-adjuvanted meningococcal C conjugated vaccine.TLR7 激动剂吸附于氢氧化铝佐剂（AS37）的辅助效应：一种 AS37 佐剂结合脑膜炎奈瑟球菌 C 疫苗的 I 期随机、剂量递增研究。
Clin Immunol. 2019 Dec;209:108275. doi: 10.1016/j.clim.2019.108275. Epub 2019 Oct 24.
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Meningococcal B vaccine (4CMenB): the journey from research to real world experience.脑膜炎 B 型疫苗（4CMenB）：从研究到真实世界经验的历程。
Expert Rev Vaccines. 2018 Dec;17(12):1111-1121. doi: 10.1080/14760584.2018.1547637. Epub 2018 Dec 5.
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Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal .比较无伤寒血清型的等效外膜囊泡和糖缀合物疫苗的免疫原性和疗效。
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A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Administered Intramuscularly to Adults from a Shigellosis-Endemic Country.一项2a期随机研究，旨在评估1790GAHB膜抗原通用模块疫苗针对来自志贺氏菌病流行国家的成年人肌肉注射给药后的安全性和免疫原性。
Front Immunol. 2017 Dec 22;8:1884. doi: 10.3389/fimmu.2017.01884. eCollection 2017.
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Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe.新型志贺氏菌血清型 5 疫苗经肌肉、皮内和鼻内途径接种的安全性特征和免疫应答：在欧洲健康成年志愿者中进行的两项平行随机 1 期临床研究结果。
EBioMedicine. 2017 Aug;22:164-172. doi: 10.1016/j.ebiom.2017.07.013. Epub 2017 Jul 15.

Editorial: Pattern recognition receptors at the crosstalk between innate and adaptive immune systems and implications for vaccine development.

作者信息

Rossi Omar, Mastroeni Pietro

机构信息

GSK Vaccines Institute for Global Health, Siena, Italy.

University of Cambridge, Cambridge, United Kingdom.

出版信息

Front Cell Infect Microbiol. 2022 Dec 2;12:1088029. doi: 10.3389/fcimb.2022.1088029. eCollection 2022.

DOI:10.3389/fcimb.2022.1088029
PMID:36530438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9755836/
Abstract
摘要