Brinnel H, Nagasaka T, Cabanac M
Intensive Care Department, Hôpital St. Joseph, Lyon, France.
Eur J Appl Physiol Occup Physiol. 1987;56(5):540-5. doi: 10.1007/BF00635367.
Selective brain cooling during hyperthermia by emissary venous pathways from the skin of the head to the brain has been reported both in animals and humans. Heat protection of the brain extends tolerance to high deep body temperature in animals, and may be enhanced in humans if the head is cooled. In order to quantify to what extent brain protection could be obtained by face fanning, 9 non-anesthetized human volunteers were placed in ambient conditions as close as possible to those of passive therapeutic hyperthermia. Face-fanning maintained tympanic temperature 0.57 degrees C lower than esophageal temperature, and improved comfort. External head cooling techniques enhancing physiological brain cooling can therefore be useful for the protection of the human brain during heat stress or passive therapeutic hyperthermia.
在动物和人类中均有报道，在热疗期间，通过从头部皮肤到大脑的导静脉途径可实现选择性脑冷却。对大脑的热保护可延长动物对深部体温过高的耐受时间，在人类中，如果头部得到冷却，这种保护作用可能会增强。为了量化面部扇风可在多大程度上实现脑保护，9名未麻醉的人类志愿者被置于尽可能接近被动治疗性热疗的环境条件下。面部扇风可使鼓膜温度比食管温度低0.57摄氏度，并改善舒适度。因此，增强生理性脑冷却的外部头部冷却技术在热应激或被动治疗性热疗期间对保护人类大脑可能是有用的。
