Faculty of Medicine, Juraj Dobrila University of Pula, Zagrebačka 30, 52100 Pula, Croatia.
Faculty of Chemical Engineering and Technology, University of Zagreb, Trg Marka Marulića 19, 10000 Zagreb, Croatia.
Molecules. 2022 Dec 7;27(24):8655. doi: 10.3390/molecules27248655.
The Mediterranean diet is recognized as a sustainable dietary approach with beneficial health effects. This is highly relevant, although the production of typical Mediterranean food, i.e., olive oil or wine, processed tomatoes and pomegranate products, generates significant amounts of waste. Ideally, this waste should be disposed in an appropriate, eco-friendly way. A number of scientific papers were published recently showing that these by-products can be exploited as a valuable source of biologically active components with health benefits, including anticancer effects. In this review, accordingly, we elaborate on such phytochemicals recovered from the food waste generated during the processing of vegetables and fruits, typical of the Mediterranean diet, with a focus on substances with anticancer activity. The molecular mechanisms of these phytochemicals, which might be included in supporting treatment and prevention of various types of cancer, are presented. The use of bioactive components from food waste may improve the economic feasibility and sustainability of the food processing industry in the Mediterranean region and can provide a new strategy to approach prevention of cancer.
地中海饮食被认为是一种可持续的饮食方法，对健康有有益的影响。这一点非常重要，尽管生产典型的地中海食品，如橄榄油或葡萄酒、加工过的西红柿和石榴产品，会产生大量的废物。理想情况下，这些废物应该以适当的、环保的方式处理。最近发表了一些科学论文，表明这些副产品可以被开发为具有健康益处的生物活性成分的有价值来源，包括抗癌作用。因此，在这篇综述中，我们详细阐述了从地中海饮食中蔬菜和水果加工过程中产生的食物废物中回收的这些植物化学物质，重点是具有抗癌活性的物质。介绍了这些植物化学物质的分子机制，它们可能被纳入对各种类型癌症的支持治疗和预防中。利用食品废物中的生物活性成分可以提高地中海地区食品加工业的经济可行性和可持续性，并为预防癌症提供新的策略。
