耳蜗健康与人工耳蜗功能。
Cochlear Health and Cochlear-implant Function.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Kresge Hearing Research Institute, University of Michigan, 1150 Medical Center Drive, Ann Arbor, MI, 48109-5616, USA.
Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Ave, Charleston, SC, 29425, USA.
出版信息
J Assoc Res Otolaryngol. 2023 Feb;24(1):5-29. doi: 10.1007/s10162-022-00882-y. Epub 2023 Jan 4.
Abstract
The cochlear implant (CI) is widely considered to be one of the most innovative and successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are able to effectively improve hearing in nearly all recipients and can substantially improve speech understanding and quality of life for patients with significant hearing loss. A wealth of research has focused on underlying factors that contribute to success with a CI, and recent evidence suggests that the overall health of the cochlea could potentially play a larger role than previously recognized. This article defines and reviews attributes of cochlear health and describes procedures to evaluate cochlear health in humans and animal models in order to examine the effects of cochlear health on performance with a CI. Lastly, we describe how future biologic approaches can be used to preserve and/or enhance cochlear health in order to maximize performance for individual CI recipients.
摘要
人工耳蜗（CI）被广泛认为是迄今为止开发的最具创新性和最成功的神经假体治疗方法之一。尽管结果因人而异，但 CI 能够有效地改善几乎所有接受者的听力，并可以大大提高有严重听力损失的患者的言语理解和生活质量。大量研究集中在有助于 CI 成功的潜在因素上，最近的证据表明，耳蜗的整体健康状况可能比以前认识到的更为重要。本文定义并回顾了耳蜗健康的属性，并描述了评估人类和动物模型耳蜗健康的程序，以研究耳蜗健康对 CI 性能的影响。最后，我们描述了如何使用未来的生物方法来保护和/或增强耳蜗健康，以最大限度地提高每个 CI 接受者的性能。
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