Hind C R, Flint K C, Hudspith B N, Felmingham D, Brostoff J, Johnson N M
Department of Medicine, Middlesex Hospital, London.
Thorax. 1987 May;42(5):332-5. doi: 10.1136/thx.42.5.332.
In a prospective study serum C-reactive protein concentrations were measured in nine patients with "active" pulmonary sarcoidosis (as assessed by bronchoalveolar lavage lymphocyte counts, gallium-67 lung scanning, and serial pulmonary function testing), and in five patients with "inactive" disease. Active pulmonary sarcoidosis was associated either with no rise or with only a modest rise in serum C-reactive protein concentrations. In contrast, serum C-reactive protein concentrations in 12 patients with sputum positive pulmonary tuberculosis were considerably raised. Serum C-reactive protein may thus provide a valuable test in the differentiation of sarcoidosis from conditions which it may mimic and which are known to induce an acute phase response.
在一项前瞻性研究中，对9例“活动性”肺结节病患者（通过支气管肺泡灌洗淋巴细胞计数、镓-67肺扫描和系列肺功能测试评估）和5例“非活动性”疾病患者测量了血清C反应蛋白浓度。活动性肺结节病患者血清C反应蛋白浓度要么没有升高，要么仅适度升高。相比之下，12例痰涂片阳性肺结核患者的血清C反应蛋白浓度显著升高。因此，血清C反应蛋白可能为鉴别结节病与可能与之相似且已知会诱导急性期反应的疾病提供一项有价值的检测。
