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青光眼高风险和低风险眼压升高患者的图形视网膜电图逆转电位

Pattern reversal retinal potentials in ocular hypertensives at high and low risk of developing glaucoma.

作者信息

Trick G L

机构信息

Department of Ophthalmology, Washington University School of Medicine, St. Louis, MO 63110.

出版信息

Doc Ophthalmol. 1987 Jan;65(1):79-85. doi: 10.1007/BF00162723.

DOI:10.1007/BF00162723
PMID:3665706
Abstract

The human pattern-reversal retinal potential (PRRP) is a bioelectrical response which reflects neural activity generated in the proximal retina. Visual diseases which affect the retinal ganglion cells and the optic nerve often produce significant reductions in the amplitude of the PRRP. PRRP amplitude reductions are frequently observed in patients with primary open-angle glaucoma. This investigation was designed to determine whether patients with ocular hypertension who are at risk of developing glaucoma also exhibit PRRP amplitude reductions. The results indicate that PRRP amplitude reductions do occur in some ocular hypertensives, but many other ocular hypertensives do not exhibit PRRP abnormalities.

摘要

人类模式反转视网膜电位(PRRP)是一种生物电反应,反映了视网膜近端产生的神经活动。影响视网膜神经节细胞和视神经的视觉疾病通常会使PRRP的振幅显著降低。原发性开角型青光眼患者经常出现PRRP振幅降低。本研究旨在确定有患青光眼风险的高眼压患者是否也存在PRRP振幅降低的情况。结果表明,一些高眼压患者确实出现了PRRP振幅降低,但许多其他高眼压患者并未表现出PRRP异常。

相似文献

1
Pattern reversal retinal potentials in ocular hypertensives at high and low risk of developing glaucoma.青光眼高风险和低风险眼压升高患者的图形视网膜电图逆转电位
Doc Ophthalmol. 1987 Jan;65(1):79-85. doi: 10.1007/BF00162723.
2
PRRP abnormalities in glaucoma and ocular hypertension.
Invest Ophthalmol Vis Sci. 1986 Dec;27(12):1730-6.
3
Retinal potentials in patients with primary open-angle glaucoma: physiological evidence for temporal frequency tuning deficits.原发性开角型青光眼患者的视网膜电位:颞部频率调谐缺陷的生理学证据。
Invest Ophthalmol Vis Sci. 1985 Dec;26(12):1750-8.
4
Pattern reversal electroretinogram (PRERG) abnormalities in ocular hypertension: correlation with glaucoma risk factors.高眼压症患者的图形视网膜电图(PRERG)异常:与青光眼危险因素的相关性
Curr Eye Res. 1988 Feb;7(2):201-6. doi: 10.3109/02713688808995749.
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Electrophysiological evidence of early functional damage in glaucoma and ocular hypertension.青光眼和高眼压症早期功能损伤的电生理学证据。
Invest Ophthalmol Vis Sci. 2010 Feb;51(2):1216-22. doi: 10.1167/iovs.09-3409. Epub 2009 Oct 22.
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[Changes in the pattern electroretinogram in glaucoma and ocular hypertension are dependent on stimulus frequency].青光眼和高眼压症中图形视网膜电图的变化取决于刺激频率
Fortschr Ophthalmol. 1991;88(5):562-5.
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Contrast sensitivity and pattern visual evoked potential in patients with glaucoma.青光眼患者的对比敏感度和图形视觉诱发电位
Doc Ophthalmol. 1987 Jan;65(1):65-70. doi: 10.1007/BF00162721.
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Pattern electroretinogram abnormality and glaucoma.图形视网膜电图异常与青光眼。
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Correlation between photopic negative response of focal electroretinograms and local loss of retinal neurons in glaucoma.青光眼局灶性视网膜电图明视负反应与局部视网膜神经元丢失的相关性。
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Evaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients, ocular hypertensives, and normal subjects.青光眼患者、眼压过高者和正常受试者的视神经乳头及视乳头周围视网膜血流评估。
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引用本文的文献

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Neuroprotective Effects of Memantine in the Retina of Glaucomatous Rats: An Electron Microscopic Study.美金刚对青光眼大鼠视网膜的神经保护作用:一项电子显微镜研究
J Ophthalmic Vis Res. 2016 Apr-Jun;11(2):174-82. doi: 10.4103/2008-322X.183934.
2
Multifocal pattern electroretinogram does not demonstrate localised field defects in glaucoma.多焦视网膜电图在青光眼患者中未显示出局限性视野缺损。
Doc Ophthalmol. 2000;100(2-3):155-65. doi: 10.1023/a:1002772520539.
3
Pilot study of the multifocal electroretinogram in ocular hypertension.高眼压症的多焦视网膜电图初步研究。

本文引用的文献

1
Electroretinographic responses to alternating gratings before and after section of the optic nerve.视神经切断前后对交替光栅的视网膜电图反应。
Science. 1981 Feb 27;211(4485):953-5. doi: 10.1126/science.7466369.
2
Specific deficits of flicker sensitivity in glaucoma and ocular hypertension.青光眼和高眼压症患者闪烁光敏感度的特定缺陷。
Invest Ophthalmol Vis Sci. 1981 Feb;20(2):204-12.
3
Interocular comparison of contrast sensitivities in glaucoma patients and suspects.青光眼患者及疑似患者对比敏感度的双眼比较。
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Mid-peripheral pattern electrical retinal responses in normals, glaucoma suspects, and glaucoma patients.正常人群、青光眼疑似患者及青光眼患者的中周边视网膜电图模式
Br J Ophthalmol. 1999 Jan;83(1):15-23. doi: 10.1136/bjo.83.1.15.
5
Little correlation of the pattern electroretinogram (PERG) and visual field measures in early glaucoma.早期青光眼患者图形视网膜电图(PERG)与视野测量结果之间的相关性较小。
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6
Primary open angle glaucomas in the rhesus monkey.恒河猴的原发性开角型青光眼
Br J Ophthalmol. 1993 May;77(5):302-10. doi: 10.1136/bjo.77.5.302.
7
Clinical applications of pattern electroretinography: melanoma, retinal detachment and glaucoma.图形视网膜电图的临床应用:黑色素瘤、视网膜脱离和青光眼。
Doc Ophthalmol. 1988 Mar-Apr;68(3-4):283-92. doi: 10.1007/BF00156434.
8
The visual evoked potential in acute primary angle closure glaucoma.急性原发性闭角型青光眼的视觉诱发电位
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9
Pattern electroretinogram recorded by skin electrodes in early ocular hypertension and glaucoma.早期高眼压症和青光眼患者经皮肤电极记录的图形视网膜电图
Doc Ophthalmol. 1989 Oct;73(2):183-91. doi: 10.1007/BF00155036.
10
Pattern electroretinogram in glaucoma and ocular hypertension.青光眼和高眼压症中的图形视网膜电图
Doc Ophthalmol. 1989 Oct;73(2):173-81. doi: 10.1007/BF00155035.
Br J Ophthalmol. 1980 Nov;64(11):858-62. doi: 10.1136/bjo.64.11.858.
4
Spectral sensitivity and color discrimination changes in glaucoma and glaucoma-suspect patients.青光眼及疑似青光眼患者的光谱敏感性和颜色辨别变化
Invest Ophthalmol Vis Sci. 1982 Oct;23(4):516-24.
5
Human pattern-evoked retinal responses are altered by optic atrophy.人类模式诱发的视网膜反应会因视神经萎缩而改变。
Invest Ophthalmol Vis Sci. 1982 Jun;22(6):796-803.
6
Loss in pattern-elicited electroretinograms in optic nerve dysfunction.
Am J Ophthalmol. 1982 Apr;93(4):418-22. doi: 10.1016/0002-9394(82)90131-3.
7
Pattern electroretinograms and visual-evoked potentials in glaucoma and multiple sclerosis.青光眼和多发性硬化症中的图形视网膜电图和视觉诱发电位
Am J Ophthalmol. 1983 Jul;96(1):72-83. doi: 10.1016/0002-9394(83)90457-9.
8
Pattern-reversal electroretinograms in unilateral glaucoma.单侧青光眼的图形翻转视网膜电图
Invest Ophthalmol Vis Sci. 1983 Jun;24(6):749-53.
9
Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma.青光眼性视乳头筛板的形态学改变与神经损伤相关。
Am J Ophthalmol. 1983 May;95(5):673-91. doi: 10.1016/0002-9394(83)90389-6.
10
The visual evoked potential in glaucoma and ocular hypertension: effects of check size, field size, and stimulation rate.青光眼和高眼压症中的视觉诱发电位:方格大小、视野范围和刺激频率的影响。
Invest Ophthalmol Vis Sci. 1983 Feb;24(2):175-83.