Hopwood V, Warnock D W, Milne J D, Crowley T, Horrocks C T, Taylor P K
Department of Microbiology, Bristol Royal Infirmary, UK.
Eur J Clin Microbiol. 1987 Aug;6(4):392-4. doi: 10.1007/BF02013092.
A new commercial slide latex particle agglutination test for rapid (2 min) diagnosis of vaginal candidosis was evaluated and compared with conventional methods. Of the 263 women studied, 63 (23.9%) had yeasts in the vagina. Clinical signs of vulvitis or vaginitis were seen in 23 women (8.8%) and 40 (15.2%) were harbouring yeasts without clinical signs. Yeast counts were generally higher in women with clinical signs of vaginal candidosis than in those without. The test was positive in 15 of the 23 women (65.2%) with clinical signs, the incidence of a positive test increasing in direct proportion to the amount of yeasts isolated. The test's sensitivity, specificity and predictive values were comparable to those of microscopy and culture. Being both rapid and simple to perform, this new test offers a useful alternative to conventional methods for the diagnosis of vaginal candidosis.
对一种用于快速(2分钟)诊断阴道念珠菌病的新型商用玻片乳胶颗粒凝集试验进行了评估,并与传统方法进行了比较。在研究的263名女性中,63名(23.9%)阴道中有酵母菌。23名女性(8.8%)出现外阴炎或阴道炎的临床症状,40名(15.2%)携带酵母菌但无临床症状。阴道念珠菌病有临床症状的女性酵母菌计数通常高于无临床症状的女性。在23名有临床症状的女性中,该试验有15名呈阳性(65.2%),阳性试验的发生率与分离出的酵母菌数量成正比增加。该试验的敏感性、特异性和预测值与显微镜检查和培养法相当。这种新试验既快速又易于操作,为阴道念珠菌病的诊断提供了一种有用的替代传统方法的手段。