Tache Irina Andra, Glotsos Dimitrios, Stanciu Silviu Marcel
Automatic Control and Systems Engineering Department, Faculty of Automatic Control and Computers, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Department of Image Fusion and Analytics, Advanta, Siemens SRL, 15 Noiembrie Bvd, 500097 Brasov, Romania.
Bioengineering (Basel). 2022 Dec 20;10(1):6. doi: 10.3390/bioengineering10010006.
The COVID-19 pandemic has produced social and economic changes that are still affecting our lives. The coronavirus is proinflammatory, it is replicating, and it is quickly spreading. The most affected organ is the lung, and the evolution of the disease can degenerate very rapidly from the early phase, also known as mild to moderate and even severe stages, where the percentage of recovered patients is very low. Therefore, a fast and automatic method to detect the disease stages for patients who underwent a computer tomography investigation can improve the clinical protocol. Transfer learning is used do tackle this issue, mainly by decreasing the computational time. The dataset is composed of images from public databases from 118 patients and new data from 55 patients collected during the COVID-19 spread in Romania in the spring of 2020. Even if the disease detection by the computerized tomography scans was studied using deep learning algorithms, to our knowledge, there are no studies related to the multiclass classification of the images into pulmonary damage stages. This could be helpful for physicians to automatically establish the disease severity and decide on the proper treatment for patients and any special surveillance, if needed. An evaluation study was completed by considering six different pre-trained CNNs. The results are encouraging, assuring an accuracy of around 87%. The clinical impact is still huge, even if the disease spread and severity are currently diminished.
新冠疫情带来了仍在影响我们生活的社会和经济变化。冠状病毒具有促炎作用,它在复制,且传播迅速。受影响最严重的器官是肺,疾病的发展可能从早期阶段,也就是所谓的轻症到中症甚至重症阶段迅速恶化,重症阶段康复患者的比例非常低。因此,一种针对接受计算机断层扫描检查的患者快速自动检测疾病阶段的方法可以改进临床方案。迁移学习被用于解决这个问题,主要是通过减少计算时间。数据集由来自118名患者的公共数据库图像以及2020年春季罗马尼亚新冠疫情期间收集的55名患者的新数据组成。即使已经使用深度学习算法对计算机断层扫描进行疾病检测的研究,但据我们所知,尚无将图像多分类到肺部损伤阶段的相关研究。这可能有助于医生自动确定疾病严重程度,并为患者决定适当的治疗方案以及必要时的任何特殊监测。通过考虑六种不同的预训练卷积神经网络完成了一项评估研究。结果令人鼓舞,准确率约为87%。即便目前疾病的传播和严重程度有所减轻,其临床影响仍然巨大。