Department of Biology and Physiology of Organisms, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, P.O. Box 32, El Alia, Bab Ezzouar, Algiers 16111, Algeria.
Laboratory of Natural Bio-Resources, Faculty of Natural and Life Sciences, Hassiba Benbouali University of Chlef, P.O. Box 151, Chlef 02000, Algeria.
Molecules. 2023 Jan 10;28(2):697. doi: 10.3390/molecules28020697.
The available phytochemical characteristics of the medicinal plants and derived herbal material often lack data concerning the content of steroids (including phytosterols) and triterpenoids, that can be responsible for various beneficial properties and therapeutic effects, either directly, or as a result of synergistic action with other bioactive constituents. The aim of the present work was the analysis of the content of these compounds in herbal material (leaves, aerial parts) derived from selected medicinal plants (, , , , , ), widely used in folk medicine in the Mediterranean region. Results obtained by gas chromatography-mass spectrometry (GC-MS)-targeted profiling revealed the diversity in the profiles and contents of steroids and triterpenoids in the analyzed plant material, ranging from 5.7% d.w. in to 0.1% in . The obtained results supplement the existing phytochemical data of the investigated medicinal plants, pointing to the aerial parts and leaves as valuable resources of phytosterols and bioactive triterpenoids.
药用植物及其衍生草药的可用植物化学成分特征通常缺乏有关类固醇(包括植物固醇)和三萜类化合物含量的数据,这些化合物可能具有各种有益特性和治疗效果,无论是直接作用,还是与其他生物活性成分协同作用的结果。本工作的目的是分析来自地中海地区民间医学中广泛使用的几种药用植物(、、、、、)的草药材料(叶、地上部分)中这些化合物的含量。通过气相色谱-质谱联用(GC-MS)靶向分析,揭示了所分析植物材料中类固醇和三萜类化合物的含量和分布存在多样性,范围从 5.7%干重的 到 0.1%的 。所得结果补充了所研究药用植物的现有植物化学数据,表明 和 的地上部分和叶是植物固醇和生物活性三萜类化合物的有价值资源。