Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia.
Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia.
Molecules. 2023 Jan 16;28(2):907. doi: 10.3390/molecules28020907.
Herein, we report the green synthesis of flower-like carrageenan-silver nanoparticles (c-AgNPs) through a facile hydrothermal reaction at 90 °C for 2 h. The reduction of silver nitrate (AgNO) to c-AgNPs was evident by the colour change of the solution from colourless to dark brown and further confirmed by a UV-Vis surface plasmon resonance (SPR) peak at ~420 nm. The FTIR spectra showed that the abundance of functional groups present in the carrageenan were responsible for the reduction and stabilisation of the c-AgNPs. The XRD pattern confirmed the crystalline nature and face-centred cubic structure of the c-AgNPs, while the EDX analysis showed the presence of a high composition of elemental silver (85.87 wt%). Interestingly, the morphological characterisations by SEM and FE-SEM revealed the formation of flower-like c-AgNPs composed of intercrossed and random lamellar petals of approximately 50 nm in thickness. The growth mechanism of flower-like c-AgNPs were elucidated based on the TEM and AFM analyses. The c-AgNPs displayed promising antibacterial properties against and , with zones of inhibition ranging from 8.0 0.0 to 11.7 ± 0.6 mm and 7.3 ± 0.6 to 9.7 ± 0.6 mm, respectively, as the concentration of c-AgNPs increased from 0.1 to 4 mg/mL.
在此，我们通过在 90°C 下进行 2 小时的简易水热反应，报告了花状卡拉胶-银纳米粒子（c-AgNPs）的绿色合成。硝酸银（AgNO）还原为 c-AgNPs 的过程可通过溶液颜色从无色变为深棕色明显看出，并进一步通过 ~420nm 的紫外-可见表面等离子体共振（SPR）峰得到证实。FTIR 光谱表明，卡拉胶中存在的大量官能团负责 c-AgNPs 的还原和稳定。XRD 图谱证实了 c-AgNPs 的结晶性质和面心立方结构，而 EDX 分析表明存在高比例的元素银（85.87wt%）。有趣的是，SEM 和 FE-SEM 的形态学特征揭示了由约 50nm 厚的交错和随机层状花瓣组成的花状 c-AgNPs 的形成。根据 TEM 和 AFM 分析，阐明了花状 c-AgNPs 的生长机制。c-AgNPs 对 和 显示出有前景的抗菌性能，随着 c-AgNPs 浓度从 0.1 增加到 4mg/mL，抑制区范围分别为 8.0 ± 0.0 至 11.7 ± 0.6mm 和 7.3 ± 0.6 至 9.7 ± 0.6mm。
