Majumder Durjoy
Department of Physiology, West Bengal State University, Kolkata, West Bengal, India.
J Med Phys. 2022 Jul-Sep;47(3):279-286. doi: 10.4103/jmp.jmp_26_22. Epub 2022 Nov 8.
Many artificial intelligence-based computational procedures are developed to diagnose COVID-19 infection from chest X-ray (CXR) images, as diagnosis by CXR imaging is less time consuming and economically cheap compared to other detection procedures. Due to unavailability of skilled computer professionals and high computer architectural resource, majority of the employed methods are difficult to implement in rural and poor economic settings. Majority of such reports are devoid of codes and ignores related diseases (pneumonia). The absence of codes makes limitation in applying them widely. Hence, validation testing followed by evidence-based medical practice is difficult. The present work was aimed to develop a simple method that requires a less computational expertise and minimal level of computer resource, but with statistical inference.
A Fast Fourier Transform-based (FFT) method was developed with GNU Octave, a free and open-source platform. This was employed to the images of CXR for further analysis. For statistical inference, two variables, i.e., the highest peak and number of peaks in the FFT distribution plot were considered.
The comparison of mean values among different groups (normal, COVID-19, viral, and bacterial pneumonia [BP]) showed statistical significance, especially when compared to normal, except between viral and BP groups.
Parametric statistical inference from our result showed high level of significance ( < 0.001). This is comparable to the available artificial intelligence-based methods (where accuracy is about 94%). Developed method is easy, availability with codes, and requires a minimal level of computer resource and can be tested with a small sample size in different demography, and hence, be implemented in a poor socioeconomic setting.
许多基于人工智能的计算程序被开发用于从胸部X线(CXR)图像诊断新型冠状病毒肺炎(COVID-19)感染,因为与其他检测程序相比,通过CXR成像进行诊断耗时更少且成本低廉。由于缺乏熟练的计算机专业人员以及计算机架构资源要求较高,大多数所采用的方法难以在农村和经济贫困地区实施。此类报告大多没有代码,并且忽略了相关疾病(肺炎)。缺少代码限制了它们的广泛应用。因此,难以进行验证测试并随后开展循证医学实践。本研究旨在开发一种简单的方法,该方法需要较少的计算专业知识和最低水平的计算机资源,但具备统计推断能力。
利用免费开源平台GNU Octave开发了一种基于快速傅里叶变换(FFT)的方法。将其应用于CXR图像以进行进一步分析。对于统计推断,考虑了两个变量,即FFT分布图中的最高峰和峰数。
不同组(正常、COVID-19、病毒性和细菌性肺炎[BP])之间的平均值比较显示出统计学意义,尤其是与正常组相比时,病毒性肺炎组和BP组之间除外。
我们结果的参数统计推断显示出高度显著性(<0.001)。这与现有的基于人工智能的方法相当(准确率约为94%)。所开发的方法简单、有代码可用,需要最低水平的计算机资源,并且可以在不同人口统计学中用小样本量进行测试,因此可在社会经济条件较差的环境中实施。