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曲霉菌感染与慢性阻塞性肺疾病。

Aspergillus infection in chronic obstructive pulmonary diseases.

机构信息

Institute of Respiratory Disease, The Second Affiliated Hospital (Xinqiao Hospital), Army Medical University, Chongqing, China.

Department of Geriatrics and Special Service medicine, The First Affiliated Hospital (Xinan Hospital), Army Medical University, Chongqing, China.

出版信息

Clin Respir J. 2023 Mar;17(3):129-138. doi: 10.1111/crj.13585. Epub 2023 Jan 29.

Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic airway non-specific inflammatory disease characterised by airway obstruction and alveolar destruction. In recent years, due to the extensive use of antibiotics, glucocorticoids, immunosuppressants and other drugs, pulmonary fungal infection in patients with AECOPD, especially aspergillus infection, has gradually increased. The forms of aspergillus infection present in COPD patients include sensitisation, chronic pulmonary aspergillosis (CPA) and invasive pulmonary aspergillosis (IPA). This review will summarise diagnostic and treatment of aspergillus in COPD patients.

摘要

慢性阻塞性肺疾病(COPD)是一种慢性气道非特异性炎症性疾病,其特征为气道阻塞和肺泡破坏。近年来,由于抗生素、糖皮质激素、免疫抑制剂等药物的广泛应用,AECOPD 患者肺部真菌感染,尤其是曲霉菌感染逐渐增多。COPD 患者曲霉菌感染的形式包括致敏、慢性肺曲霉病(CPA)和侵袭性肺曲霉病(IPA)。本文就 COPD 患者曲霉菌感染的诊断和治疗进行综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92e/9978918/9cdf1c5823bb/CRJ-17-129-g003.jpg

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