Talebi Ardakani Mohamadreza, Farahi Atiyeh, Mojab Faraz, Moscowchi Anahita, Gharazi Zahra
Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Restorative Dentistry, School of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
J Adv Periodontol Implant Dent. 2022 Oct 8;14(2):109-113. doi: 10.34172/japid.2022.017. eCollection 2022.
Recent advances in alternative medicine have led to the introduction of various new herbal products for treating gingivitis as the most prevalent gingival disease. The present study clinically evaluated the effect of a herbal mouthwash consisting of 5 herbal extracts (Myrtus communis, Quercus brantii, Punica granatum, Portulaca olerace, and Boswellia serrata) on periodontal indices. Fifty patients with plaque-induced gingivitis were included in this randomized, dou-ble-blinded clinical trial and divided into two groups. Following scaling and root planing (SRP), they were prescribed 0.2% chlorhexidine (CHX) (group 1) and herbal mouthwash (group 2) twice a day for 14 days. Both groups received saline mouthwash for the subsequent 14 days (wash-out time). Then, they used the mouthwashes in a cross-over manner for an additional two weeks. Probing pocket depth (PPD), gingival index (GI), bleeding on probing (BOP), and plaque index (PI) were recorded at baseline and after each period of mouthwash use. The data were analyzed by SPSS software, using generalized estimating equation (GEE) linear regression and paired t-test. P<0.05 was considered sta-tistically significant. Both groups exhibited statistically significant improvements in the periodontal indices compared to the baseline (P<0.05); however, there were no significant differences between the two study groups in this regard. The experimental herbal mouthwash improved the periodontal condition in plaque-induced gingivitis after two weeks, comparable to the effect of %0.2 CHX mouthwash in terms of PPD, BOP, PI, and GI.
替代医学的最新进展促使各种新型草药产品问世，用于治疗最为常见的牙龈疾病——牙龈炎。本研究对一种由5种草药提取物（香桃木、无梗花栎、石榴、马齿苋和乳香）组成的草药漱口水对牙周指数的影响进行了临床评估。50例菌斑性牙龈炎患者被纳入这项随机双盲临床试验，并分为两组。在进行龈下刮治和根面平整（SRP）后，他们被规定每天两次使用0.2%氯己定（CHX）（第1组）和草药漱口水（第2组），持续14天。在随后的14天（洗脱期），两组均使用生理盐水漱口水。然后，他们以交叉方式再使用两周漱口水。在基线以及每次使用漱口水一段时间后，记录探诊深度（PPD）、牙龈指数（GI）、探诊出血（BOP）和菌斑指数（PI）。数据使用SPSS软件，通过广义估计方程（GEE）线性回归和配对t检验进行分析。P<0.05被认为具有统计学意义。与基线相比，两组的牙周指数均有统计学意义的改善（P<0.05）；然而，在这方面两个研究组之间没有显著差异。实验性草药漱口水在两周后改善了菌斑性牙龈炎的牙周状况，在PPD、BOP、PI和GI方面与0.2%CHX漱口水的效果相当。
