The Third Xiangya Hospital of Central South University, Central South University, Changsha, China.
Xiangya Stomatological Hospital & School of Stomatology, Central South University, Changsha, China.
BMC Oral Health. 2023 Feb 1;23(1):61. doi: 10.1186/s12903-023-02761-1.
Inflammation and oxidative stress are two hallmarks of periodontitis. Retinol is an antioxidant and suppresses expression of pro-inflammatory factors. However, the evidence for an association between retinol intake and periodontitis is limited. Thus, the aim of this study is to assess the association between retinol intake and periodontal health.
Data used in this cross-sectional study from the National Health and Nutrition Examination Survey (NHANES) 2009-2014 (n = 9081). Dietary intake of retinol was measured based on two 24-h dietary recall interviews. The category of periodontitis was defined by the CDC/AAP according to clinical periodontal parameters. Univariate and multivariate logistic regression analyses were applied to investigate the relationship between retinol intake and the risk of periodontitis.
Compared with the lowest tertile, individuals in the highest tertile of retinol intake were less likely to be periodontitis (OR = 0.79, 95% CI: 0.65-0.96). The association was still significant in populations who were less than 60 years old (OR = 0.80, 95% CI: 0.65-0.97), non-Hispanic black (OR = 0.62, 95% CI: 0.42-0.94), PI ≤ 1.3 (OR = 0.72, 95% CI: 0.55-0.93), 1.3 < PI ≤ 3.5 (OR = 0.70, 95% CI: 0.55-0.89), non-smoker (OR = 0.63, 95% CI: 0.48-0.81), obesity (OR = 0.68, 95% CI: 0.49-0.94) and who had not diabetes mellitus (OR = 0.79, 95% CI: 0.65-0.95) or had hypertension (OR = 0.63, 95% CI: 0.47-0.84).
Retinol intake is inversely associated with poor periodontal health in US adults.
炎症和氧化应激是牙周炎的两个标志。视黄醇是一种抗氧化剂，可抑制促炎因子的表达。然而，视黄醇摄入与牙周炎之间的关联证据有限。因此，本研究旨在评估视黄醇摄入与牙周健康之间的关系。
本横断面研究使用了 2009-2014 年全国健康与营养调查（NHANES）的数据（n=9081）。视黄醇的饮食摄入量基于两次 24 小时饮食回忆访谈进行测量。根据临床牙周参数，疾病预防控制中心/美国牙周病学会（CDC/AAP）定义了牙周炎的类别。应用单变量和多变量逻辑回归分析来研究视黄醇摄入与牙周炎风险之间的关系。
与最低三分位相比，视黄醇摄入最高三分位的个体患牙周炎的可能性较低（OR=0.79，95%CI：0.65-0.96）。在年龄小于 60 岁的人群（OR=0.80，95%CI：0.65-0.97）、非西班牙裔黑人（OR=0.62，95%CI：0.42-0.94）、PI≤1.3（OR=0.72，95%CI：0.55-0.93）、1.3<PI≤3.5（OR=0.70，95%CI：0.55-0.89）、不吸烟者（OR=0.63，95%CI：0.48-0.81）、肥胖者（OR=0.68，95%CI：0.49-0.94）和没有糖尿病（OR=0.79，95%CI：0.65-0.95）或高血压（OR=0.63，95%CI：0.47-0.84）的人群中，这种关联仍然显著。
视黄醇摄入与美国成年人牙周健康状况不佳呈负相关。
