活的和标准化钩端螺旋体显微镜凝集试验的比较。

A comparison of live and formalised leptospiral microscopic agglutination test.

作者信息

Palmer M F, Waitkins S A, Wanyangu S W

机构信息

PHLS Leptospira Reference Unit/WHO/FAO Collaborating Centre for Research and Reference on Leptospirosis, County Hospital, Hereford, United Kingdom.

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Jun;265(1-2):151-9. doi: 10.1016/s0176-6724(87)80161-x.

DOI:10.1016/s0176-6724(87)80161-x

PMID:3673329

Abstract

The sensitivity and reliability of a formalised leptospiral antigen battery was compared with a smaller battery of live leptospiral antigens with 152 human sera positive for leptospirosis. There was good concurrence of results between the formalised and live antigens, however the live battery did fail to detect some positive sera where the antibody level was low. The formalised antigens were more sensitive than the live (P less than 0.001) and more reliable in the detection of early leptospiral infection, but the live antigens were more specific in the determination of probable infecting serogroup.

摘要

将一组标准化的钩端螺旋体抗原与一组数量较少的活钩端螺旋体抗原进行了敏感性和可靠性比较，检测对象为152份钩端螺旋体病阳性的人血清。标准化抗原和活抗原的检测结果有较好的一致性，然而，活抗原组确实未能检测出一些抗体水平较低的阳性血清。标准化抗原在检测早期钩端螺旋体感染方面比活抗原更敏感（P小于0.001）且更可靠，但活抗原在确定可能的感染血清群方面更具特异性。