Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
Food Chem. 2023 Jun 30;412:135589. doi: 10.1016/j.foodchem.2023.135589. Epub 2023 Jan 27.
In-depth studies of the extraction mechanism using deep eutectic solvents (DES), especially extraction through the formation of a deep eutectic system (DESys), revealed commonalities between the DES- and ionic liquids (IL)-based extraction systems. New applications of ILs and DES for extraction of nutritional natural products were presented. In this study, the extraction behavior of choline chloride (ChCl) and 1-(2-hydroxyethyl)-3-methylimidazolium chloride ([HMIm][Cl]) in DES and IL, respectively, in mechanochemical extraction of target compounds from Moringa oleifera leaves was systematically studied. The results suggested that both extraction methods were based on the formation of a DESys, either a normal DESys or an IL DESys. Considering the DESys-based one-step extraction improves the extraction efficiency and reduces the preparation time, the same idea can be used in IL for performance improvement. By formation of a new IL deep eutectic system based on hydrogen bond interaction in extraction, similar improvement was obtained.
深入研究了使用深共晶溶剂 (DES) 的提取机制，特别是通过形成深共晶体系 (DESys) 的提取，揭示了 DES 和基于离子液体 (IL) 的提取系统之间的共同之处。介绍了 IL 和 DES 在提取营养天然产物方面的新应用。在这项研究中，系统研究了胆碱氯化物 (ChCl) 和 1-(2-羟乙基)-3-甲基咪唑氯化物 ([HMIm][Cl]) 在机械化学提取辣木叶中目标化合物时分别在 DES 和 IL 中的提取行为。结果表明，这两种提取方法均基于 DESys 的形成，无论是常规 DESys 还是 IL DESys。考虑到基于 DESys 的一步提取可提高提取效率并缩短制备时间，因此相同的想法可用于 IL 以提高性能。通过在提取过程中形成基于氢键相互作用的新型 IL 深共晶体系，获得了类似的改善。
