Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Cell. 2023 Feb 2;186(3):461-463. doi: 10.1016/j.cell.2023.01.006.
Magnetic spins, pendulum clocks, and fireflies all self-organize into coherent collectives when arranged into groups of spatially coupled and interacting individuals. Ramanathan and colleagues demonstrate that spatial coupling of human stem cell organoids induces coherent progression through developmental transitions, allowing the dissection of molecular circuits underlying human development.
当磁性旋转体、钟摆时钟和萤火虫被排列成具有空间耦合和相互作用的个体群体时,它们都会自行组织成相干的集体。Ramanathan 及其同事证明,人类干细胞类器官的空间耦合诱导了发育转变的相干进展,从而能够剖析人类发育的分子回路。