Neural Circuits, Consciousness and Cognition Research Group, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.
Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America.
PLoS One. 2023 Feb 10;18(2):e0268577. doi: 10.1371/journal.pone.0268577. eCollection 2023.
The relationship between conscious experience and brain activity has intrigued scientists and philosophers for centuries. In the last decades, several theories have suggested different accounts for these relationships. These theories have developed in parallel, with little to no cross-talk among them. To advance research on consciousness, we established an adversarial collaboration between proponents of two of the major theories in the field, Global Neuronal Workspace and Integrated Information Theory. Together, we devised and preregistered two experiments that test contrasting predictions of these theories concerning the location and timing of correlates of visual consciousness, which have been endorsed by the theories' proponents. Predicted outcomes should either support, refute, or challenge these theories. Six theory-impartial laboratories will follow the study protocol specified here, using three complementary methods: Functional Magnetic Resonance Imaging (fMRI), Magneto-Electroencephalography (M-EEG), and intracranial electroencephalography (iEEG). The study protocol will include built-in replications, both between labs and within datasets. Through this ambitious undertaking, we hope to provide decisive evidence in favor or against the two theories and clarify the footprints of conscious visual perception in the human brain, while also providing an innovative model of large-scale, collaborative, and open science practice.
意识体验与大脑活动之间的关系引起了科学家和哲学家几个世纪以来的兴趣。在过去的几十年里,几种理论对这些关系提出了不同的解释。这些理论平行发展,彼此之间几乎没有交流。为了推进意识研究,我们在该领域的两个主要理论的支持者之间建立了一个对抗性的合作关系,即全局神经元工作空间理论和综合信息理论。我们共同设计并预先注册了两项实验,这些实验检验了这些理论对视觉意识相关物的位置和时间的对比预测,这些预测得到了理论支持者的认可。预期结果要么支持、反驳或挑战这些理论。六个理论中立的实验室将按照这里规定的研究方案进行研究,使用三种互补的方法:功能磁共振成像(fMRI)、磁脑电图(M-EEG)和颅内脑电图(iEEG)。研究方案将包括内置的复制,包括实验室之间和数据集内的复制。通过这项雄心勃勃的任务,我们希望提供决定性的证据来支持或反对这两个理论,并阐明意识视觉感知在人类大脑中的痕迹,同时提供大规模、协作和开放科学实践的创新模型。