日本九州南部败血症牛和猪源化脓隐秘杆菌的药敏试验。
Antimicrobial susceptibility of Trueperella pyogenes isolated from cattle and pigs with septicemia in southern Kyushu, Japan.
机构信息
Shibushi Meat Inspection Center, Kagoshima Prefecture, Kagoshima, Japan.
Kanoya Meat Inspection Center, Kagoshima Prefecture, Kagoshima, Japan.
出版信息
J Vet Med Sci. 2023 Mar 28;85(3):379-382. doi: 10.1292/jvms.22-0460. Epub 2023 Mar 10.
We investigated the antimicrobial susceptibility of Trueperella pyogenes isolates from cattle and pigs diagnosed with septicemia at slaughter. The strains investigated in this study were found to be susceptible to ampicillin, cefazolin, gentamicin, and levofloxacin. However, 53.3% of the strains were resistant to tetracycline, 49.7% to streptomycin, 13.8% to erythromycin, 13.2% to clindamycin, and 1.2% to oxacillin and kanamycin. We also found that the resistance of pig-derived strains of T. pyogenes to tetracycline, streptomycin, erythromycin, and clindamycin was higher than that of cattle-derived strains, and these strains were resistant to up to four antimicrobial agents used simultaneously. The present results provide new data on the range of the minimum inhibitory concentration (MIC) values of various antimicrobial agents for T. pyogenes isolated from livestock with septicemia. The breakpoint values used in this study are generally considered applicable.
我们研究了从屠宰时患有败血症的牛和猪中分离出的化脓隐秘杆菌的药敏性。本研究中调查的菌株对氨苄西林、头孢唑林、庆大霉素和左氧氟沙星敏感。然而，53.3%的菌株对四环素耐药，49.7%对链霉素耐药，13.8%对红霉素耐药，13.2%对克林霉素耐药，1.2%对苯唑西林和卡那霉素耐药。我们还发现，猪源化脓隐秘杆菌对四环素、链霉素、红霉素和克林霉素的耐药性高于牛源菌株，这些菌株对多达四种同时使用的抗菌药物具有耐药性。本研究为化脓隐秘杆菌对不同抗菌药物的最低抑菌浓度（MIC）值范围提供了新的数据，这些数据可用于患有败血症的牲畜。本研究中使用的折点值通常被认为是适用的。
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