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嗜肺军团菌:临床和环境分离株的单克隆抗体分型

Legionella pneumophila: monoclonal antibody typing of clinical and environmental isolates.

作者信息

Brindle R J, Stannett P J, Tobin J O

机构信息

Public Health Laboratory, John Radcliffe Hospital, Headington, Oxford.

出版信息

Epidemiol Infect. 1987 Oct;99(2):235-9. doi: 10.1017/s0950268800067698.

Abstract

Forty-one clinical isolates of Legionella pneumophila from sporadic cases of legionella pneumonia were collected from laboratories throughout the United Kingdom and were compared with 300 routine environmental isolates using two panels of monoclonal antibodies, covering serogroups 1-10. Eighty-five per cent of the clinical isolates belonged to the subgroup Pontiac of serogroup 1, whilst only 13% of the environmental isolates did. Approximately half of the clinical isolates tested came from patients with a recent history of foreign travel, mainly to southern Europe.

摘要

从英国各地实验室收集了41株来自军团菌肺炎散发病例的嗜肺军团菌临床分离株,并使用两组单克隆抗体(覆盖血清群1-10)将其与300株常规环境分离株进行比较。85%的临床分离株属于血清群1的庞蒂亚克亚群,而环境分离株中只有13%属于该亚群。约一半接受检测的临床分离株来自近期有国外旅行史的患者,主要前往南欧。

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Nosocomial Legionnaires' disease--advances in diagnosis and typing.
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本文引用的文献

3
Genetic structure of populations of Legionella pneumophila.嗜肺军团菌群体的遗传结构。
J Bacteriol. 1985 Sep;163(3):1021-37. doi: 10.1128/jb.163.3.1021-1037.1985.

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