衰弱与心血管死亡率：叙事性综述。
Frailty and Cardiovascular Mortality: A Narrative Review.
机构信息
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Section of Cardiovascular Medicine, Boston Medical Center, Boston University School of Medicine, Boston, USA.
出版信息
Curr Cardiol Rep. 2023 Apr;25(4):249-259. doi: 10.1007/s11886-023-01847-0. Epub 2023 Feb 16.
Abstract
PURPOSE OF REVIEW
The goal of the narrative review is to provide an overview of the epidemiology of frailty in cardiovascular disease and cardiovascular mortality and discuss applications of frailty in cardiovascular care of older adults.
RECENT FINDINGS
Frailty is highly prevalent in older adults with cardiovascular disease and is a robust, independent predictor of cardiovascular death. There is a growing interest in using frailty to inform management of cardiovascular disease either through pre- or post-treatment prognostication or by delineating treatment heterogeneity in which frailty serves to distinguish patients with differential harms or benefits from a given therapy. Frailty can enable more individualized treatment in older adults with cardiovascular disease. Future studies are needed to standardize frailty assessment across cardiovascular trials and enable implementation of frailty assessment in cardiovascular clinical practice.
摘要
目的综述
本综述旨在概述心血管疾病和心血管死亡率方面的虚弱症流行病学，并讨论虚弱症在老年人心血管护理中的应用。
最新发现
虚弱症在患有心血管疾病的老年人中非常普遍，是心血管死亡的一个强有力的独立预测因素。人们越来越感兴趣地使用虚弱症来为心血管疾病的管理提供信息，无论是通过治疗前或治疗后预后，还是通过描述治疗异质性，虚弱症可以区分患者对特定治疗的不同危害或获益。虚弱症可以使老年心血管疾病患者的治疗更加个体化。未来的研究需要标准化心血管试验中的虚弱评估，并在心血管临床实践中实施虚弱评估。
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