• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于心电图灰度图像和标度图协同训练的双模态卷积神经网络心血管疾病分类方法。

Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms.

机构信息

Department of Healthcare Information Technology, Inje University, Inje-ro, Gimhae-si, 50834, Republic of Korea.

出版信息

Sci Rep. 2023 Feb 20;13(1):2937. doi: 10.1038/s41598-023-30208-8.

DOI:10.1038/s41598-023-30208-8
PMID:36804469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9941114/
Abstract

This study aimed to develop a bimodal convolutional neural network (CNN) by co-training grayscale images and scalograms of ECG for cardiovascular disease classification. The bimodal CNN model was developed using a 12-lead ECG database collected from Chapman University and Shaoxing People's Hospital. The preprocessed database contains 10,588 ECG data and 11 heart rhythms labeled by a specialist physician. The preprocessed one-dimensional ECG signals were converted into two-dimensional grayscale images and scalograms, which are fed simultaneously to the bimodal CNN model as dual input images. The proposed model aims to improve the performance of CVDs classification by making use of ECG grayscale images and scalograms. The bimodal CNN model consists of two identical Inception-v3 backbone models, which were pre-trained on the ImageNet database. The proposed model was fine-tuned with 6780 dual-input images, validated with 1694 dual-input images, and tested on 2114 dual-input images. The bimodal CNN model using two identical Inception-v3 backbones achieved best AUC (0.992), accuracy (95.08%), sensitivity (0.942), precision (0.946) and F1-score (0.944) in lead II. Ensemble model of all leads obtained AUC (0.994), accuracy (95.74%), sensitivity (0.950), precision (0.953), and F1-score (0.952). The bimodal CNN model showed better diagnostic performance than logistic regression, XGBoost, LSTM, single CNN model training with grayscale images alone or with scalograms alone. The proposed bimodal CNN model would be of great help in diagnosing cardiovascular diseases.

摘要

本研究旨在开发一种双模态卷积神经网络(CNN),通过对心电图的灰度图像和谱图进行联合训练,实现心血管疾病分类。该双模态 CNN 模型是使用查普曼大学和绍兴人民医院采集的 12 导联心电图数据库开发的。预处理后的数据库包含 10588 份心电图数据和 11 种由专家医生标记的心律。预处理后的一维心电图信号被转换为二维灰度图像和谱图,作为双输入图像同时输入到双模态 CNN 模型中。所提出的模型旨在通过利用心电图灰度图像和谱图来提高 CVD 分类的性能。双模态 CNN 模型由两个相同的 Inception-v3 骨干模型组成,这些模型是在 ImageNet 数据库上预训练的。该模型使用 6780 对双输入图像进行微调,使用 1694 对双输入图像进行验证,并使用 2114 对双输入图像进行测试。使用两个相同的 Inception-v3 骨干的双模态 CNN 模型在导联 II 中达到了最佳 AUC(0.992)、准确率(95.08%)、敏感度(0.942)、精度(0.946)和 F1 分数(0.944)。所有导联的集成模型获得了 AUC(0.994)、准确率(95.74%)、敏感度(0.950)、精度(0.953)和 F1 分数(0.952)。与逻辑回归、XGBoost、LSTM、仅使用灰度图像或仅使用谱图进行单 CNN 模型训练相比,双模态 CNN 模型显示出更好的诊断性能。所提出的双模态 CNN 模型将有助于诊断心血管疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/d658ea2d40e5/41598_2023_30208_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/5c7e6e12a059/41598_2023_30208_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/4afaf76e1065/41598_2023_30208_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/d658ea2d40e5/41598_2023_30208_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/5c7e6e12a059/41598_2023_30208_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/4afaf76e1065/41598_2023_30208_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a48/9941114/d658ea2d40e5/41598_2023_30208_Fig3_HTML.jpg

相似文献

1
Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms.基于心电图灰度图像和标度图协同训练的双模态卷积神经网络心血管疾病分类方法。
Sci Rep. 2023 Feb 20;13(1):2937. doi: 10.1038/s41598-023-30208-8.
2
Multi-Modal Stacking Ensemble for the Diagnosis of Cardiovascular Diseases.用于心血管疾病诊断的多模态堆叠集成方法
J Pers Med. 2023 Feb 20;13(2):373. doi: 10.3390/jpm13020373.
3
A novel proposed CNN-SVM architecture for ECG scalograms classification.一种用于心电图波谱图分类的新型卷积神经网络-支持向量机架构。
Soft comput. 2023;27(8):4639-4658. doi: 10.1007/s00500-022-07729-x. Epub 2022 Dec 15.
4
Performance of a Convolutional Neural Network and Explainability Technique for 12-Lead Electrocardiogram Interpretation.卷积神经网络性能及 12 导联心电图解释的可解释性技术。
JAMA Cardiol. 2021 Nov 1;6(11):1285-1295. doi: 10.1001/jamacardio.2021.2746.
5
A Hybrid Deep CNN Model for Abnormal Arrhythmia Detection Based on Cardiac ECG Signal.基于心脏 ECG 信号的异常心律失常检测的混合深度卷积神经网络模型。
Sensors (Basel). 2021 Feb 1;21(3):951. doi: 10.3390/s21030951.
6
Obstructive sleep apnea prediction from electrocardiogram scalograms and spectrograms using convolutional neural networks.基于卷积神经网络的心电图谱图和声谱图对阻塞性睡眠呼吸暂停的预测。
Physiol Meas. 2021 Jun 29;42(6). doi: 10.1088/1361-6579/ac0a9c.
7
Development and Validation of a Convolutional Neural Network Model to Predict a Pathologic Fracture in the Proximal Femur Using Abdomen and Pelvis CT Images of Patients With Advanced Cancer.利用晚期癌症患者腹部和骨盆 CT 图像建立卷积神经网络模型预测股骨近端病理性骨折的研究
Clin Orthop Relat Res. 2023 Nov 1;481(11):2247-2256. doi: 10.1097/CORR.0000000000002771. Epub 2023 Aug 23.
8
Noise Eliminated Ensemble Empirical Mode Decomposition Scalogram Analysis for Rotating Machinery Fault Diagnosis.基于去噪集成经验模态分解谱图分析的旋转机械故障诊断
Sensors (Basel). 2021 Dec 4;21(23):8114. doi: 10.3390/s21238114.
9
Lightweight Multireceptive Field CNN for 12-Lead ECG Signal Classification.用于 12 导联心电图信号分类的轻量级多感受野 CNN。
Comput Intell Neurosci. 2022 Aug 8;2022:8413294. doi: 10.1155/2022/8413294. eCollection 2022.
10
Performance of a convolutional neural network derived from an ECG database in recognizing myocardial infarction.基于心电图数据库的卷积神经网络在识别心肌梗死中的性能。
Sci Rep. 2020 May 21;10(1):8445. doi: 10.1038/s41598-020-65105-x.

引用本文的文献

1
BlendNet: a blending-based convolutional neural network for effective deep learning of electrocardiogram signals.BlendNet:一种基于融合的卷积神经网络,用于心电图信号的有效深度学习。
Front Artif Intell. 2025 Aug 22;8:1625637. doi: 10.3389/frai.2025.1625637. eCollection 2025.
2
Robust screening of atrial fibrillation with distribution classification.基于分布分类的房颤稳健筛查
Sci Rep. 2025 Jul 22;15(1):26582. doi: 10.1038/s41598-025-10090-2.
3
A Machine Learning Approach to Microcalorimetric Pattern Classification of Pathogens in Synovial Fluid.

本文引用的文献

1
A deep learning framework assisted echocardiography with diagnosis, lesion localization, phenogrouping heterogeneous disease, and anomaly detection.深度学习框架辅助超声心动图进行诊断、病变定位、表型分组和异常检测。
Sci Rep. 2023 Jan 2;13(1):3. doi: 10.1038/s41598-022-27211-w.
2
A Hybrid Deep Learning Approach for ECG-Based Arrhythmia Classification.一种基于心电图的心律失常分类的混合深度学习方法。
Bioengineering (Basel). 2022 Apr 2;9(4):152. doi: 10.3390/bioengineering9040152.
3
Convolutional neural network for classification of eight types of arrhythmia using 2D time-frequency feature map from standard 12-lead electrocardiogram.
一种用于滑液中病原体微量热模式分类的机器学习方法。
J Orthop Res. 2025 Oct;43(10):1855-1864. doi: 10.1002/jor.70024. Epub 2025 Jul 13.
4
Efficient pretraining of ECG scalogram images using masked autoencoders for cardiovascular disease diagnosis.使用掩码自动编码器对心电图小波图图像进行高效预训练以用于心血管疾病诊断。
Sci Rep. 2025 Jul 8;15(1):24444. doi: 10.1038/s41598-025-10773-w.
5
Arrhythmia classification based on multi-input convolutional neural network with attention mechanism.基于带有注意力机制的多输入卷积神经网络的心律失常分类
PLoS One. 2025 Jun 17;20(6):e0326079. doi: 10.1371/journal.pone.0326079. eCollection 2025.
6
Design and validation of a novel multiple sites signal acquisition and analysis system based on pressure stimulation for human cardiovascular information.基于压力刺激的人体心血管信息新型多部位信号采集与分析系统的设计与验证
Sci Rep. 2025 Apr 18;15(1):13392. doi: 10.1038/s41598-025-97812-8.
7
Deep learning for electrocardiogram interpretation: Bench to bedside.用于心电图解读的深度学习:从实验室到临床应用
Eur J Clin Invest. 2025 Apr;55 Suppl 1(Suppl 1):e70002. doi: 10.1111/eci.70002.
8
ECG heartbeat classification using progressive moving average transform.基于渐进移动平均变换的心电图心跳分类
Sci Rep. 2025 Feb 4;15(1):4285. doi: 10.1038/s41598-025-88119-9.
9
Research on a Lightweight Arrhythmia Classification Model Based on Knowledge Distillation for Wearable Single-Lead ECG Monitoring Systems.基于知识蒸馏的可穿戴单导联心电图监测系统轻量级心律失常分类模型研究
Sensors (Basel). 2024 Dec 10;24(24):7896. doi: 10.3390/s24247896.
10
Cardioish: Lead-Based Feature Extraction for ECG Signals.Cardioish:用于心电图信号的基于导联的特征提取
Diagnostics (Basel). 2024 Nov 30;14(23):2712. doi: 10.3390/diagnostics14232712.
卷积神经网络使用标准 12 导联心电图的 2D 时频特征图对 8 种心律失常进行分类。
Sci Rep. 2021 Oct 14;11(1):20396. doi: 10.1038/s41598-021-99975-6.
4
ECG-based machine-learning algorithms for heartbeat classification.基于心电图的心跳分类机器学习算法。
Sci Rep. 2021 Sep 21;11(1):18738. doi: 10.1038/s41598-021-97118-5.
5
A new deep learning algorithm of 12-lead electrocardiogram for identifying atrial fibrillation during sinus rhythm.一种新的 12 导联心电图深度学习算法,用于在窦性节律期间识别心房颤动。
Sci Rep. 2021 Jun 17;11(1):12818. doi: 10.1038/s41598-021-92172-5.
6
Binomial Classification of Pediatric Elbow Fractures Using a Deep Learning Multiview Approach Emulating Radiologist Decision Making.使用深度学习多视图方法模拟放射科医生决策的小儿肘部骨折二项式分类
Radiol Artif Intell. 2019 Jan 30;1(1):e180015. doi: 10.1148/ryai.2019180015. eCollection 2019 Jan.
7
PTB-XL, a large publicly available electrocardiography dataset.PTB-XL,一个大型的公开可用的心电图数据集。
Sci Data. 2020 May 25;7(1):154. doi: 10.1038/s41597-020-0495-6.
8
Application of deep learning techniques for heartbeats detection using ECG signals-analysis and review.深度学习技术在利用心电图信号进行心跳检测中的应用——分析与综述
Comput Biol Med. 2020 May;120:103726. doi: 10.1016/j.compbiomed.2020.103726. Epub 2020 Apr 8.
9
Assessing cardiovascular risks from a mid-thigh CT image: a tree-based machine learning approach using radiodensitometric distributions.基于 CT 图像股中部评估心血管风险:使用放射密度分布的基于树的机器学习方法。
Sci Rep. 2020 Feb 18;10(1):2863. doi: 10.1038/s41598-020-59873-9.
10
A 12-lead electrocardiogram database for arrhythmia research covering more than 10,000 patients.一个包含超过 10000 名患者的心律失常研究用 12 导联心电图数据库。
Sci Data. 2020 Feb 12;7(1):48. doi: 10.1038/s41597-020-0386-x.