Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran.
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran.
Biosensors (Basel). 2023 Feb 1;13(2):216. doi: 10.3390/bios13020216.
(L.M.) is a gram-positive bacillus with wide distribution in the environment. This bacterium contaminates water sources and food products and can be transmitted to the human population. The infection caused by L.M. is called listeriosis and is common in pregnant women, immune-deficient patients, and older adults. Based on the released statistics, listeriosis has a high rate of hospitalization and mortality; thus, rapid and timely detection of food contamination and listeriosis cases is necessary. During the last few decades, biosensors have been used for the detection and monitoring of varied bacteria species. These devices are detection platforms with great sensitivity and low detection limits. Among different types of biosensors, electrochemical biosensors have a high capability to circumvent several drawbacks associated with the application of conventional laboratory techniques. In this review article, different electrochemical biosensor types used for the detection of listeriosis were discussed in terms of actuators, bioreceptors, specific working electrodes, and signal amplification. We hope that this review will facilitate researchers to access a complete and comprehensive template for pathogen detection based on the different formats of electrochemical biosensors.
（L.M.）是一种革兰氏阳性杆菌，广泛分布于环境中。这种细菌污染水源和食品，并可能传播给人类。由 L.M.引起的感染称为李斯特菌病，常见于孕妇、免疫功能低下的患者和老年人。根据公布的数据，李斯特菌病的住院率和死亡率很高；因此，快速及时地检测食物污染和李斯特菌病病例是必要的。在过去几十年中，生物传感器已被用于检测和监测各种细菌。这些设备是具有高灵敏度和低检测限的检测平台。在不同类型的生物传感器中，电化学生物传感器具有克服与传统实验室技术应用相关的许多缺点的高能力。在这篇综述文章中，根据电化学生物传感器的不同格式，讨论了用于检测李斯特菌病的不同类型的电化学生物传感器，包括作动器、生物受体、特定工作电极和信号放大。我们希望这篇综述将有助于研究人员根据电化学生物传感器的不同格式访问用于病原体检测的完整和全面的模板。
