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胸腔感染

Pleural Space Infections.

作者信息

Foley Sean P F, Parrish John Scott

机构信息

Department of Pulmonary, Critical Care and Sleep Medicine, Naval Medical Center San Diego, San Diego, CA 92134, USA.

出版信息

Life (Basel). 2023 Jan 29;13(2):376. doi: 10.3390/life13020376.

DOI:10.3390/life13020376
PMID:36836732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9959801/
Abstract

Pleural space infections have been a well-recognized clinical syndrome for over 4000 years and continue to cause significant morbidity and mortality worldwide. However, our collective understanding of the causative pathophysiology has greatly expanded over the last few decades, as have our treatment options. The aim of this paper is to review recent updates in our understanding of this troublesome disease and to provide updates on established and emerging treatment modalities for patients suffering from pleural space infections. With that, we present a review and discussion synthesizing the recent pertinent literature surrounding the history, epidemiology, pathophysiology, diagnosis, and management of these challenging infections.

摘要

胸腔感染作为一种已被广泛认知的临床综合征已有4000多年的历史,在全球范围内仍导致显著的发病率和死亡率。然而,在过去几十年里,我们对其致病病理生理学的总体认识有了极大的扩展,治疗选择也是如此。本文旨在回顾我们对这种棘手疾病认识的最新进展,并为患有胸腔感染的患者提供关于既定和新兴治疗方式的最新信息。在此,我们对围绕这些具有挑战性感染的历史、流行病学、病理生理学、诊断和管理的近期相关文献进行综述和讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ce/9959801/590bee27c57a/life-13-00376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ce/9959801/45ef044aa7b4/life-13-00376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ce/9959801/590bee27c57a/life-13-00376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ce/9959801/45ef044aa7b4/life-13-00376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ce/9959801/590bee27c57a/life-13-00376-g002.jpg

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Pleural Space Infections.胸腔感染
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[Parapneumonic pleural effusions: Epidemiology, diagnosis, classification and management].[类肺炎性胸腔积液:流行病学、诊断、分类及管理]
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Pleural Empyema in Spain (2016-2022): A Nationwide Study on Trends in Hospitalizations, Mortality, and Impact of Comorbidities.西班牙的胸膜脓胸(2016 - 2022年):一项关于住院治疗趋势、死亡率及合并症影响的全国性研究
J Pers Med. 2025 Jun 20;15(7):263. doi: 10.3390/jpm15070263.
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Missed Foreign Body Aspiration: Fentanyl Patch Leading to Severe Pneumonia and Empyema.

本文引用的文献

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ERS/ESTS statement on the management of pleural infection in adults.欧洲呼吸学会/欧洲心胸外科学会关于成人胸膜感染管理的声明。
Eur Respir J. 2023 Feb 2;61(2). doi: 10.1183/13993003.01062-2022. Print 2023 Feb.
2
Comparing Initial Surgery versus Fibrinolytics for Pleural Space Infections: A Retrospective Multicenter Cohort Study.比较胸腔空间感染的初始手术与纤溶治疗:一项回顾性多中心队列研究。
Ann Am Thorac Soc. 2022 Nov;19(11):1827-1833. doi: 10.1513/AnnalsATS.202108-964OC.
3
The bacteriology of pleural infection (TORPIDS): an exploratory metagenomics analysis through next generation sequencing.
异物误吸:芬太尼透皮贴导致严重肺炎和脓胸。
Cureus. 2025 Jan 24;17(1):e77931. doi: 10.7759/cureus.77931. eCollection 2025 Jan.
4
Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine Guidelines: Benign Pleura Lesions (Benign Pleura Thickening, Lesions and Masses)-What Can Be Seen on Transthoracic Ultrasound?欧洲医学超声学会指南评注与说明:良性胸膜病变(良性胸膜增厚、病变及肿块)——经胸超声能看到什么?
Diagnostics (Basel). 2025 Jan 14;15(2):176. doi: 10.3390/diagnostics15020176.
5
Pleural space infection microbiology as assessed using a clinical sequencing-based assay: group, and other oral normal microbiota are the most common bacteria identified in community-acquired pleural space infections.使用基于临床测序的检测方法评估的胸膜腔感染微生物学:在社区获得性胸膜腔感染中,厌氧菌和其他口腔正常微生物群是最常见的细菌。
J Clin Microbiol. 2024 Dec 11;62(12):e0069424. doi: 10.1128/jcm.00694-24. Epub 2024 Nov 25.
6
Challenging Diagnosis of Streptococcus intermedius-Associated Empyema in an Immunocompetent Adult: A Case Report and Literature Review.免疫功能正常的成年人中间型链球菌相关性脓胸的疑难诊断:病例报告及文献综述
Cureus. 2024 May 17;16(5):e60482. doi: 10.7759/cureus.60482. eCollection 2024 May.
7
Immunoassay with Novel Paired Antibodies for Detection of Lipoarabinomannan in the Pleural Fluid and Plasma of Patients with Tuberculous Pleurisy.用新型配对抗体免疫测定法检测结核性胸膜炎患者胸腔积液和血浆中的脂阿拉伯甘露聚糖
Microorganisms. 2023 Sep 8;11(9):2259. doi: 10.3390/microorganisms11092259.
胸腔感染的细菌学(TORPIDS):通过下一代测序进行的探索性宏基因组分析。
Lancet Microbe. 2022 Apr;3(4):e294-e302. doi: 10.1016/S2666-5247(21)00327-X. Epub 2022 Mar 11.
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BMJ Open. 2022 Mar 9;12(3):e054236. doi: 10.1136/bmjopen-2021-054236.
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Nicotinamide phosphoribosyltransferase as a biomarker for the diagnosis of infectious pleural effusions.烟酰胺磷酸核糖基转移酶作为感染性胸腔积液诊断的生物标志物。
Sci Rep. 2021 Oct 26;11(1):21121. doi: 10.1038/s41598-021-00653-4.
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Int J Gen Med. 2021 Jul 14;14:3415-3429. doi: 10.2147/IJGM.S292705. eCollection 2021.
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Chest. 2021 Oct;160(4):1534-1551. doi: 10.1016/j.chest.2021.05.026. Epub 2021 May 20.
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BMC Pulm Med. 2021 Apr 20;21(1):127. doi: 10.1186/s12890-021-01492-9.
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CT appearances of pleural infection: analysis of the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) cohort.胸膜感染的 CT 表现:第二多中心胸膜内脓毒症试验(MIST 2)队列分析。
Clin Radiol. 2021 Jun;76(6):436-442. doi: 10.1016/j.crad.2020.12.017. Epub 2021 Apr 2.