School of Medicine, Anhui Xinhua University, 555 Wangjiang West Road, Hefei 230088, China.
Molecules. 2023 Feb 10;28(4):1713. doi: 10.3390/molecules28041713.
, also known as "gold in plants" because of the famous agents with emphases on Taxol and Docetaxel, is a genus of the family Taxaceae, distributed almost around the world. The plants hold an important place in traditional medicine in China, and its products are used for treating treat dysuria, swelling and pain, diabetes, and irregular menstruation in women. In order to make a further study and better application of plants for the future, cited references from between 1958 and 2022 were collected from the Web of Science, the China National Knowledge Internet (CNKI), SciFinder, and Google Scholar, and the chemical structures, distribution, and bioactivity of flavonoids identified from samples were summed up in the research. So far, 59 flavonoids in total with different skeletons were identified from plants, presenting special characteristics of compound distribution. These compounds have been reported to display significant antibacterial, antiaging, anti-Alzheimer's, antidiabetes, anticancer, antidepressant, antileishmaniasis, anti-inflammatory, antinociceptive and antiallergic, antivirus, antilipase, neuronal protective, and hepatic-protective activities, as well as promotion of melanogenesis. Flavonoids represent a good example of the utilization of the species. In the future, further pharmacological and clinical experiments for flavonoids could be accomplished to promote the preparation of relative drugs.
, 也被称为“植物中的黄金”，因为其著名的有效成分包括紫杉醇和多西他赛，是 Taxaceae 科的一个属，分布几乎遍及全球。该属植物在中国传统医学中占有重要地位，其产品用于治疗尿频、肿胀和疼痛、糖尿病和妇女月经不调。为了进一步研究和更好地应用 植物，本研究从 1958 年至 2022 年期间，从 Web of Science、中国国家知识网（CNKI）、SciFinder 和 Google Scholar 等数据库中收集了参考文献，总结了从 种植物中鉴定出的类黄酮的化学结构、分布和生物活性。迄今为止，已从 植物中鉴定出 59 种具有不同骨架的类黄酮，呈现出化合物分布的特殊特征。这些化合物已被报道具有显著的抗菌、抗衰老、抗阿尔茨海默病、抗糖尿病、抗癌、抗抑郁、抗利什曼病、抗炎、镇痛、抗过敏、抗病毒、脂肪酶抑制、神经保护和肝保护活性，以及促进黑色素生成。类黄酮是利用 属植物的一个很好的例子。未来可以进行进一步的类黄酮药理学和临床实验，以促进相关药物的制备。
