Gomez-Hinostroza E Sebastian, Gurdo Nicolás, Alvan Vargas María Victoria Gracia, Nikel Pablo I, Guazzaroni María-Eugenia, Guaman Linda P, Castillo Cornejo David J, Platero Raúl, Barba-Ostria Carlos
Laboratorio de Investigación en Citogenética y Biomoléculas de Anfibios (LICBA), Centro de Investigación para la Salud en América Latina (CISeAL), Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs Lyngby, Denmark.
Front Bioeng Biotechnol. 2023 Feb 10;11:1069628. doi: 10.3389/fbioe.2023.1069628. eCollection 2023.
Synthetic biology (SynBio) is a rapidly advancing multidisciplinary field in which South American countries such as Chile, Argentina, and Brazil have made notable contributions and have established leadership positions in the region. In recent years, efforts have strengthened SynBio in the rest of the countries, and although progress is significant, growth has not matched that of the aforementioned countries. Initiatives such as iGEM and TECNOx have introduced students and researchers from various countries to the foundations of SynBio. Several factors have hindered progress in the field, including scarce funding from both public and private sources for synthetic biology projects, an underdeveloped biotech industry, and a lack of policies to promote bio-innovation. However, open science initiatives such as the DIY movement and OSHW have helped to alleviate some of these challenges. Similarly, the abundance of natural resources and biodiversity make South America an attractive location to invest in and develop SynBio projects.
合成生物学是一个迅速发展的多学科领域，智利、阿根廷和巴西等南美国家在该领域做出了显著贡献，并在该地区确立了领先地位。近年来，其他国家也在加强合成生物学方面的工作，尽管取得了重大进展，但发展速度仍不及上述国家。国际基因工程机器大赛（iGEM）和TECNOx等项目让各国的学生和研究人员了解了合成生物学的基础。该领域的发展受到了几个因素的阻碍，包括公共和私人来源对合成生物学项目的资金稀缺、生物技术产业不发达以及缺乏促进生物创新的政策。然而，像DIY运动和开源硬件（OSHW）这样的开放科学举措有助于缓解其中一些挑战。同样，丰富的自然资源和生物多样性使南美洲成为投资和开展合成生物学项目的有吸引力的地点。
