Departamento de Bioquímica, Centro de Biociências, CB, Universidade Federal de Pernambuco (UFPE), Avenida Professor Moraes Rego, S/N, Cidade Universitária, Recife, Pernambuco, Brazil.
Departamento de Saúde, Faculdade Santa Maria, Cajazeiras, Paraíba, Brazil.
Biotechnol Appl Biochem. 2023 Aug;70(4):1504-1517. doi: 10.1002/bab.2455. Epub 2023 Apr 10.
Actinomycetes are a distinct group of filamentous bacteria. The Streptomyces genus within this group has been extensively studied over the years, with substantial contributions to society and science. This genus is known for its antimicrobial production, as well as antitumor, biopesticide, and immunomodulatory properties. Therefore, the extraordinary plasticity of the Streptomyces genus has inspired new research techniques. The newest way of exploring Streptomyces has comprised the discovery of new natural metabolites and the application of emerging tools such as CRISPR technology in drug discovery. In this narrative review, we explore relevant published literature concerning the ongoing novelties of the Streptomyces genus.
放线菌是一类独特的丝状细菌。该类群中的链霉菌属多年来得到了广泛研究，为社会和科学做出了巨大贡献。该属以其抗菌产物以及抗肿瘤、生物农药和免疫调节特性而闻名。因此，链霉菌属的非凡可塑性激发了新的研究技术。探索链霉菌的最新方法包括发现新的天然代谢物以及在药物发现中应用新兴工具，如 CRISPR 技术。在这篇叙述性综述中，我们探讨了有关链霉菌属最新进展的相关已发表文献。
