Gudmundsdóttir Sigrídur Lára, Ballarini Tommaso, Ámundadóttir María L, Mészáros Judit, Eysteinsdottir Jenna Huld, Thorleifsdottir Ragna H, Hrafnkelsdóttir Sigrídur K, Helgadottir Halla, Oddsson Saemundur, Silverberg Jonathan I
Sidekick Health Digital Therapeutics, Kopavogur, Iceland.
Department of Health Promotion, Sport and Leisure Studies, University of Iceland, Reykjavik, Iceland.
JMIR Form Res. 2023 Jun 14;7:e41227. doi: 10.2196/41227.
Patients with atopic dermatitis can experience chronic eczema with pruritus, skin pain, sleep problems, anxiety, and other problems that reduce their quality of life (QoL). Current treatments aim to improve these symptoms and reduce inflammation, but poor treatment adherence and disease understanding are key concerns in the long-term management of atopic dermatitis. Digital therapeutics can help with these and support patients toward a healthier lifestyle to improve their overall QoL.
The aim of the study is to test the feasibility of a digital health program tailored for atopic dermatitis through program engagement, retention, and acceptability.
Adults with atopic dermatitis were recruited in Iceland for a 6-week digital health program delivered through a smartphone app. Key components of the digital program were disease and trigger education; medication reminders; patient-reported outcomes (PROs) on energy levels, stress levels, and quality of sleep (referred to as QoL PROs); atopic dermatitis symptom PROs; guided meditation; and healthy lifestyle coaching. The primary outcome was program feasibility, as assessed by in-app retention and engagement. User satisfaction was assessed by the mHealth (ie, mobile health) App Usability Questionnaire (MAUQ).
A total of 21 patients were recruited (17 female, mean age 31 years), 20 (95%) completed the program. On average, users were active in the app 6.5 days per week and completed 8.2 missions per day. The education content, medication reminders, and PROs had high user engagement and retention; all users who were exposed to the QoL PROs (n=17) interacted with these, and 20/21 (95%) users were continuously engaged with the education missions, medication missions, and symptom PROs. Continued engagement with the step counter and mind missions among exposed users was lower (17/21 and 13/20 participants, respectively). Medication reminder and education task completion remained high over time (at least 18/20, 90%), but weekly interactions declined. All assigned users completed atopic dermatitis symptom PROs on weeks 1-5 and only one did not do so on week 6; the reported number and total severity of atopic dermatitis symptoms reduced during the program. Regarding the QoL PROs, 16/17 (94%) and 14/17 (82%) users interacted with these at least 3 times in the first and last week of the program, respectively, and all reported improvements over time. User satisfaction was high with a total score of 6.2/7.
We found high overall engagement and retention in a targeted digital health program among patients with atopic dermatitis, as well as high compliance with missions relating to medication reminders, patient education, and PROs. Symptom number and severity were reduced, and QoL PROs improved over time. We conclude that a digital health program is feasible and may provide added benefits for patients with atopic dermatitis, including the tracking and improvement of atopic dermatitis symptoms.
特应性皮炎患者可能会经历伴有瘙痒、皮肤疼痛、睡眠问题、焦虑及其他问题的慢性湿疹,这些问题会降低他们的生活质量(QoL)。目前的治疗旨在改善这些症状并减轻炎症,但治疗依从性差和对疾病的了解不足是特应性皮炎长期管理中的关键问题。数字疗法有助于解决这些问题,并支持患者养成更健康的生活方式,以提高他们的整体生活质量。
本研究的目的是通过项目参与度、留存率和可接受性来测试针对特应性皮炎量身定制的数字健康项目的可行性。
在冰岛招募患有特应性皮炎的成年人,参与一项通过智能手机应用程序提供的为期6周的数字健康项目。该数字项目的关键组成部分包括疾病和触发因素教育;用药提醒;患者报告的关于能量水平、压力水平和睡眠质量的结果(称为生活质量患者报告结果);特应性皮炎症状患者报告结果;引导式冥想;以及健康生活方式指导。主要结果是项目可行性,通过应用程序内的留存率和参与度来评估。用户满意度通过移动健康(即mHealth)应用程序可用性问卷(MAUQ)进行评估。
共招募了21名患者(17名女性,平均年龄31岁),20名(95%)完成了该项目。平均而言,用户每周在应用程序中活跃6.5天,每天完成8.2项任务。教育内容(、用药提醒和患者报告结果具有较高的用户参与度和留存率;所有接触过生活质量患者报告结果的用户(n = 17)都与之互动,20/21(95%)的用户持续参与教育任务、用药任务和症状患者报告结果。接触过的用户中,步数计数器和心理任务的持续参与度较低(分别为17/21和13/20参与者)。随着时间的推移,用药提醒和教育任务的完成率仍然很高(至少18/20,90%),但每周的互动次数有所下降。所有指定用户在第1 - 第5周都完成了特应性皮炎症状患者报告结果,只有一名用户在第6周未完成;在项目期间,报告的特应性皮炎症状数量和严重程度有所减少。关于生活质量患者报告结果,16/17(94%)和14/17(82%)的用户在项目的第一周和最后一周分别至少与这些结果互动3次,并且所有用户都报告随着时间的推移有所改善。用户满意度很高,总分为6.2/7。
我们发现针对特应性皮炎患者的目标数字健康项目具有较高的整体参与度和留存率,以及与用药提醒、患者教育和患者报告结果相关任务的高依从性。症状数量和严重程度有所减少,生活质量患者报告结果随着时间的推移有所改善。我们得出结论,数字健康项目是可行的,并且可能为特应性皮炎患者提供额外的益处,包括跟踪和改善特应性皮炎症状。