Graduate School of Fisheries and Environmental Sciences, Nagasaki University, 1-14, Bunkyo-Machi, Nagasaki 852-8521, Japan.
Toxins (Basel). 2023 Mar 3;15(3):193. doi: 10.3390/toxins15030193.
The xanhid crab and the blue-lined octopus cf. have long been known as TTX-bearing organisms. It has been speculated that the TTX possessed by both organisms is exogenously toxic through the food chain, since they are reported to have geographic and individual differences. The source and supply chain of TTX for both of these organisms, however, remain unclear. On the other hand, since crabs are one of the preferred prey of octopuses, we focused our attention on the relationship between the two species living in the same site. The aim of this study was to determine TTX concentrations and TTX profiles of and cf. , collected simultaneously in the same site, and examine the relationship between them. Although there were individual differences in the TTX concentration in both and cf. the toxin components commonly contained 11-TTX-6()-ol in addition to TTX as the major components, with 4-TTX, 11-deoxyTTX, and 4,9-anhydroTTX as the minor components. The results suggest that octopuses and crabs in this site acquire TTX from common prey, including TTX-producing bacteria and/or may have a predator-prey relationship.
青蟹和蓝环章鱼 cf. 一直以来都被认为是含有 TTX 的生物体。据报道，这两种生物在地理和个体上存在差异，因此人们推测它们所携带的 TTX 是通过食物链从外部摄入的有毒物质。然而，这两种生物的 TTX 来源和供应链仍不清楚。另一方面，由于螃蟹是章鱼的首选猎物之一，我们将注意力集中在生活在同一地点的两种生物之间的关系上。本研究的目的是确定在同一地点同时采集的 和 cf. 中的 TTX 浓度和 TTX 谱，并研究它们之间的关系。尽管 和 cf. 中的 TTX 浓度存在个体差异，但毒素成分通常除了 TTX 作为主要成分外，还含有 11-TTX-6()-ol，作为次要成分，还含有 4-TTX、11-去氧 TTX 和 4,9-脱水 TTX。结果表明，该地点的章鱼和螃蟹从共同的猎物中获取 TTX，包括产生 TTX 的细菌和/或可能存在捕食者-猎物关系。
