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用于检测毒性生物战剂的免疫传感器。

Immunosensors for Assay of Toxic Biological Warfare Agents.

机构信息

Faculty of Military Health Sciences, University of Defense, Trebesska 1575, CZ-50001 Hradec Kralove, Czech Republic.

出版信息

Biosensors (Basel). 2023 Mar 20;13(3):402. doi: 10.3390/bios13030402.

Abstract

An immunosensor for the assay of toxic biological warfare agents is a biosensor suitable for detecting hazardous substances such as aflatoxin, botulinum toxin, ricin, Shiga toxin, and others. The application of immunosensors is used in outdoor assays, point-of-care tests, as a spare method for more expensive devices, and even in the laboratory as a standard analytical method. Some immunosensors, such as automated flow-through analyzers or lateral flow tests, have been successfully commercialized as tools for toxins assay, but the research is ongoing. New devices are being developed, and the use of advanced materials and assay techniques make immunosensors highly competitive analytical devices in the field of toxic biological warfare agents assay. This review summarizes facts about current applications and new trends of immunosensors regarding recent papers in this area.

摘要

一种用于检测有毒生物战剂的免疫传感器是一种适用于检测黄曲霉毒素、肉毒杆菌毒素、蓖麻毒素、志贺毒素等有害物质的生物传感器。免疫传感器的应用包括户外检测、即时检测、作为更昂贵设备的备用方法,甚至在实验室中作为标准分析方法。一些免疫传感器,如自动化流动分析仪或横向流动测试,已经成功商业化,作为毒素检测工具,但研究仍在继续。新的设备正在开发中,先进的材料和检测技术的使用使免疫传感器在有毒生物战剂检测领域成为极具竞争力的分析设备。本综述总结了该领域近期论文中有关免疫传感器的当前应用和新趋势的事实。

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