State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, 210023, Nanjing, China.
Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, 201800, Shanghai, China.
Nat Commun. 2023 Mar 29;14(1):1745. doi: 10.1038/s41467-023-37333-y.
High-entropy multimetallic nanopatterns with controlled morphology, composition and uniformity hold great potential for developing nanoelectronics, nanophotonics and catalysis. Nevertheless, the lack of general methods for patterning multiple metals poses a limit. Here, we develop a DNA origami-based metallization reaction system to prescribe multimetallic nanopatterns with peroxidase-like activities. We find that strong coordination between metal elements and DNA bases enables the accumulation of metal ions on protruding clustered DNA (pcDNA) that are prescribed on DNA origami. As a result of the condensation of pcDNA, these sites can serve as nucleation site for metal plating. We have synthesized multimetallic nanopatterns composed of up to five metal elements (Co, Pd, Pt, Ag and Ni), and obtained insights on elemental uniformity control at the nanoscale. This method provides an alternative pathway to construct a library of multimetallic nanopatterns.
具有可控形态、组成和均一性的高熵多金属纳米图案在发展纳米电子学、纳米光子学和催化方面具有巨大潜力。然而，缺乏对多种金属进行图案化的通用方法是一个限制。在这里，我们开发了一种基于 DNA 折纸术的金属化反应系统，以规定具有过氧化物酶样活性的多金属纳米图案。我们发现，金属元素与 DNA 碱基之间的强配位作用使得金属离子能够在 DNA 折纸术上规定的突出聚集 DNA (pcDNA)上积累。由于 pcDNA 的缩合，这些位点可以作为金属镀覆的成核位点。我们已经合成了由多达五种金属元素（Co、Pd、Pt、Ag 和 Ni）组成的多金属纳米图案，并在纳米尺度上获得了元素均匀性控制的见解。该方法为构建多金属纳米图案库提供了一种替代途径。
