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中国感染艾滋病毒的男男性行为者对猴痘的认知及疫苗接种意愿:一项横断面研究

Perception of and Vaccine Readiness towards Mpox among Men Who Have Sex with Men Living with HIV in China: A Cross-Sectional Study.

作者信息

Fu Leiwen, Sun Yinghui, Li Yuwei, Wang Bingyi, Yang Luoyao, Tian Tian, Wu Xinsheng, Peng Xin, Liu Qi, Chen Yuanyi, Lin Yi-Fan, Li Hui, Meng Xiaojun, Zou Huachun

机构信息

School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.

Center for Disease Control and Prevention, Shizhong District, Jinan 250004, China.

出版信息

Vaccines (Basel). 2023 Feb 23;11(3):528. doi: 10.3390/vaccines11030528.

Abstract

BACKGROUND

Men who have sex with men (MSM) living with HIV make up the majority of cases in the current Mpox outbreak. We aimed to investigate the perception of and vaccine readiness towards Mpox among MSM living with HIV in China.

METHODS

This cross-sectional online study was conducted from 10 August to 9 September 2022. Participants responded to survey questions about their socio-demographic information, HIV status, sexual behaviors, knowledge of Mpox, and attitudes towards Mpox vaccines.

RESULTS

A total of 577 MSM living with HIV participated in the study. A total of 37.6% expressed concerns about the Mpox epidemic in China, and 56.8% were willing to get the Mpox vaccine. Men who had > four sexual partners in the previous three months (aOR = 1.9 95% CI: 1.2-2.8 Ref: 0), had close contact with > four individuals in a day (3.1, 1.5-6.5 Ref: 0-3), were worried about the Mpox epidemic in China (1.6, 1.1-2.3 Ref: No), and believed that Mpox vaccines are safe (6.6, 2.7-16.4 Ref: No or not sure) and effective (1.9, 1.1-3.3 Ref: No) for people living with HIV were more likely to be willing to get the Mpox vaccine. MSM living with HIV with a high school education or below (0.5, 0.3-0.9 Ref: Postgraduate diploma), and sometimes (0.5, 0.3-0.8 Ref: Often), seldom, or never (0.5, 0.3-0.9 Ref: Often) followed news about Mpox were unwilling to get the Mpox vaccine.

CONCLUSION

The ongoing Mpox pandemic has not attracted widespread concerns among MSM living with HIV in China. Having more sexual partners and close contacts, worrying about the Mpox epidemic, and believing in the vaccine's safety and efficacy were predictors of their willingness to get the Mpox vaccine. Efforts should be made to raise awareness of the potential risk of Mpox in this at-risk population. Public health strategies should fully address predictors of vaccination willingness.

摘要

背景

在当前的猴痘疫情中,感染艾滋病毒的男男性行为者(MSM)占病例的大多数。我们旨在调查中国感染艾滋病毒的男男性行为者对猴痘的认知以及接种疫苗的意愿。

方法

这项横断面在线研究于2022年8月10日至9月9日进行。参与者回答了有关其社会人口统计学信息、艾滋病毒状况、性行为、猴痘知识以及对猴痘疫苗态度的调查问题。

结果

共有577名感染艾滋病毒的男男性行为者参与了该研究。共有37.6%的人对中国的猴痘疫情表示担忧,56.8%的人愿意接种猴痘疫苗。在过去三个月中有超过四个性伴侣的男性(调整后比值比[aOR]=1.9,95%置信区间[CI]:1.2 - 2.8;参照组:0)、一天内与超过四个人密切接触的男性(3.1,1.5 - 6.5;参照组:0 - 3)、担心中国猴痘疫情的男性(1.6,1.1 - 2.3;参照组:否)以及认为猴痘疫苗对感染艾滋病毒的人安全(6.6,2.7 - 16.4;参照组:否或不确定)且有效的男性(1.9,1.1 - 3.3;参照组:否)更有可能愿意接种猴痘疫苗。高中及以下学历的感染艾滋病毒的男男性行为者(0.5,0.3 - 0.9;参照组:研究生学历)以及有时(0.5,0.3 - 0.8;参照组:经常)、很少或从不(0.5,0.3 - 0.9;参照组:经常)关注猴痘新闻的人不愿意接种猴痘疫苗。

结论

当前的猴痘大流行在中国感染艾滋病毒的男男性行为者中尚未引起广泛关注。有更多性伴侣和密切接触者、担心猴痘疫情以及相信疫苗的安全性和有效性是他们愿意接种猴痘疫苗的预测因素。应努力提高这一高危人群对猴痘潜在风险的认识。公共卫生策略应充分考虑接种意愿的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d27/10059946/b6ad4fc9be6c/vaccines-11-00528-g001.jpg

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