State Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia.
Institute of Systematics and Ecology of Animals, 630091 Novosibirsk, Russia.
Viruses. 2022 Feb 2;14(2):309. doi: 10.3390/v14020309.
To date, six hantavirus species have been detected in moles (family Talpidae). In this report, we describe Academ virus (ACDV), a novel hantavirus harbored by the Siberian mole () in Western Siberia. Genetic analysis of the complete S-, M-, and partial L-genomic segments showed that ACDV shared a common evolutionary origin with Bruges virus, previously identified in the European mole (), and is distantly related to other mole-borne hantaviruses. Co-evolution and local adaptation of genetic variants of hantaviruses and their hosts, with possible reassortment events, might have shaped the evolutionary history of ACDV.
迄今为止，已在鼹鼠科（family Talpidae）中发现了六种汉坦病毒。在本报告中，我们描述了一种新型汉坦病毒——科学院病毒（ACDV），该病毒存在于西西伯利亚的西伯利亚鼹鼠（）中。对完整的 S、M 和部分 L 基因组片段的遗传分析表明，ACDV 与先前在欧洲鼹鼠（）中发现的布鲁日病毒（Bruges virus）具有共同的进化起源，与其他鼹鼠携带的汉坦病毒关系较远。汉坦病毒及其宿主的遗传变异的共同进化和局部适应，可能伴随着重组事件，这些可能塑造了 ACDV 的进化历史。
