Chandrasekhar Giddigari, Shukla Manjulika, Kaul Grace, K Rekha, Chopra Sidharth, Pandey Richa
Centre for Natural Products and Traditional Knowledge, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
J Asian Nat Prod Res. 2023 Nov;25(11):1110-1116. doi: 10.1080/10286020.2023.2193698. Epub 2023 Apr 3.
Chemical investigation of roots of the plant, Linn, led to the isolation of an undescribed anthraquinone, cordifoquinone R, determined as 1,2-dihydroxy-6-methoxyanthracene-9,10-dione ( based on the 1D and 2D NMR analyses and HRESIMS. Ten other known compounds 1,4-dihydroxy-2-methoxyanthracene-9,10-dione (), rubiadin (), xanthopurpurin (), 1-methoxy-3-hydroxy-2-carbomethoxy-9,10-anthraquinone (), alizarin (), β-sitosterol glucoside (), scopoletin (), oleanolic acid, (), pomolic acid (), queretaroic acid () were also isolated. Out of these compounds, , , and are first reported from this plant species. Compounds and showed activity in the range of 16-32 µg/ml against ATCC 29213.
对该植物（林奈）根部进行化学研究，从中分离出一种未描述的蒽醌类化合物，即cordifoquinone R，经一维和二维核磁共振分析以及高分辨电喷雾电离质谱测定其为1,2 - 二羟基 - 6 - 甲氧基蒽醌 - 9,10 - 二酮。还分离出了其他十种已知化合物，分别为1,4 - 二羟基 - 2 - 甲氧基蒽醌 - 9,10 - 二酮、玉红菌素、1 - 甲氧基 - 3 - 羟基 - 2 - 甲氧基羰基 - 9,10 - 蒽醌、茜素、β - 谷甾醇葡萄糖苷、东莨菪素、齐墩果酸、坡模酸、奎雷塔罗酸。在这些化合物中，、和首次从该植物物种中报道。化合物和对ATCC 29213显示出16 - 32微克/毫升范围内的活性。
