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J Am Soc Nephrol. 2019 Oct;30(10):1968-1979. doi: 10.1681/ASN.2019020144. Epub 2019 Sep 5.
3
Computational Segmentation and Classification of Diabetic Glomerulosclerosis.糖尿病肾小球硬化的计算分割与分类。
J Am Soc Nephrol. 2019 Oct;30(10):1953-1967. doi: 10.1681/ASN.2018121259. Epub 2019 Sep 5.
4
CNN cascades for segmenting sparse objects in gigapixel whole slide images.CNN 级联用于分割千兆像素全幻灯片图像中的稀疏对象。
Comput Med Imaging Graph. 2019 Jan;71:40-48. doi: 10.1016/j.compmedimag.2018.11.002. Epub 2018 Nov 16.
5
Deep Learning Global Glomerulosclerosis in Transplant Kidney Frozen Sections.深度学习移植肾冷冻切片中的全球肾小球硬化症。
IEEE Trans Med Imaging. 2018 Dec;37(12):2718-2728. doi: 10.1109/TMI.2018.2851150. Epub 2018 Jun 27.
6
Deep learning for digital pathology image analysis: A comprehensive tutorial with selected use cases.用于数字病理学图像分析的深度学习:包含选定用例的全面教程。
J Pathol Inform. 2016 Jul 26;7:29. doi: 10.4103/2153-3539.186902. eCollection 2016.
7
Brain tumor segmentation with Deep Neural Networks.基于深度神经网络的脑肿瘤分割。
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New Trends of Emerging Technologies in Digital Pathology.数字病理学中新兴技术的新趋势
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Measurement of glomerulus diameter and Bowman's space width of renal albino rats.测量白化病大鼠肾小球直径和鲍曼氏囊腔宽度。
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Segmental HOG: new descriptor for glomerulus detection in kidney microscopy image.分段方向梯度直方图:用于肾脏显微镜图像中肾小球检测的新描述符。
BMC Bioinformatics. 2015 Sep 30;16:316. doi: 10.1186/s12859-015-0739-1.

使用分割神经网络进行肾小球检测。

Glomerulus Detection Using Segmentation Neural Networks.

机构信息

Department of Computer Science and Engineering, Graphic Era (Deemed to be University), Dehradun, 248002, Uttarkhand, India.

Department of Electronics and Communication Engineering, Indian Institute of Information Technology, Dharwad, Karnataka, 580009, India.

出版信息

J Digit Imaging. 2023 Aug;36(4):1633-1642. doi: 10.1007/s10278-022-00764-y. Epub 2023 Apr 5.

DOI:10.1007/s10278-022-00764-y
PMID:37020148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10406769/
Abstract

Digital pathology is vital for the correct diagnosis of kidney before transplantation or kidney disease identification. One of the key challenges in kidney diagnosis is glomerulus detection in kidney tissue segments. In this study, we propose a deep learning-based method for glomerulus detection from digitized kidney slide segments. The proposed method applies models based on convolutional neural networks to detect image segments containing the glomerulus region. We employ various networks such as ResNets, UNet, LinkNet, and EfficientNet to train the models. In our experiments on a network trained on the NIH HuBMAP kidney whole slide image dataset, the proposed method achieves the highest scores with Dice coefficient of 0.942.

摘要

数字病理学对于肾脏移植前的正确诊断或肾脏疾病的识别至关重要。肾脏诊断中的一个关键挑战是在肾脏组织切片中检测肾小球。在这项研究中,我们提出了一种基于深度学习的方法,用于从数字化肾脏切片中检测肾小球。所提出的方法应用基于卷积神经网络的模型来检测包含肾小球区域的图像段。我们使用各种网络,如 ResNets、UNet、LinkNet 和 EfficientNet 来训练模型。在我们对在 NIH HuBMAP 肾脏全幻灯片图像数据集上训练的网络进行的实验中,所提出的方法在 Dice 系数为 0.942 时取得了最高得分。